“INTRODUCTION TO BIOINFORMATICS” by (Aqsad)

1. “INTRODUCTION TO BIOINFORMATICS” • by • (Aqsad)

2. What is Bioinformatics? Bioinformatics = Biology + Information Biology is becoming an information science. Computational methods are necessary to analyze the Massive amount of information that are coming out of the genome projects.

3. What is Bioinformatics? Easy Answer - Using computers to solve molecular biology problems Hard Answer - Computational techniques for management and analysis of biological data and knowledge.

4. Bioinformatics • Bioinformatics: is the development and use of computer applications for the Analysis, Interpretation, and Prediction of biological Systems and corresponding experimental methods in nature sciences.

5. Bioinformatics bridges many disciplines Bioinformatics combines the tools of Biology, Chemistry, Mathematics, Statistics and Computer Science to understand Life & its processes.

6. 6 Bioinformatics HISTORY Physics & Chemistry, 1950s Molecular Biology Biology Biochemistry Biophysics Margaret Dayhoff Computer Sc. & Statistics, 1970s Bioinformatics

7. Biological Data and Bioinformatics. NAILS = DATA Hammer = BIOINFORMATICS

8. What is bioinformatics? •   Main goal is to convert complex data into information and knowledge •   Data includes gene and protein sequences, nucleotide sequences . •   Information used to build synthetic and predictive models. •   Future applications in biology, chemistry, pharmaceuticals, medicine, and agriculture

9. genes, proteins, protein complexes, pathways, cells,organisms, ecosystem Bioinformatics:Studying Biology on Computer data management; data mining; modeling; prediction; theory formulation. bioinformatics scientific aspect Computer system

10. Discovery from Data Mining (I)

11. DNA - Sequence .....acctc ctgtgcaaga acatgaaaca cctgtggttc ttccttctcc tggtggcagc tcccagatgg gtcctgtccc aggtgcacct gcaggagtcg ggcccaggac tggggaagcc tccagagctc aaaaccccac ttggtgacac aactcacaca tgcccacggt gcccagagcc caaatcttgt gacacacctc ccccgtgccc acggtgccca gagcccaaat cttgtgacac acctccccca tgcccacggt gcccagagcc caaatcttgt gacacacctc ccccgtgccc ccggtgccca gcacctgaac tcttgggagg accgtcagtc ttcctcttcc ccccaaaacc caaggatacc cttatgattt cccggacccc tgaggtcacg tgcgtggtgg tggacgtgag ccacgaagac cccgaggtcc agttcaagtg gtacgtggac ggcgtggagg tgcataatgc caagacaaag ctgcgggagg agcagtacaa cagcacgttc cgtgtggtca gcgtcctcac cgtcctgcac caggactggc tgaacggcaa ggagtacaag tgcaaggtct ccaacaaagc aaccaagtca gcctgacctg cctggtcaaa ggcttctacc ccagcgacat cgccgtggag tgggagagca atgggcagcc ggagaacaac tacaacacca cgcctcccat gctggactcc gacggctcct tcttcctcta cagcaagctc accgtggaca agagcaggtg gcagcagggg aacatcttct catgctccgt gatgcatgag gctctgcaca accgctacac gcagaagagc ctctc.....

12. THANKS