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Palamine, M.T, Armada, F., Jimenez, R. Locnen, SA. , Magsombol,EB., and Calleja, HB.

EXTRACORPOREAL SH0CKWAVE MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH ISCHEMIC HEART DISEASE: THE ST. LUKE’S EXPERIENCE. Palamine, M.T, Armada, F., Jimenez, R. Locnen, SA. , Magsombol,EB., and Calleja, HB. St. Luke’s Heart Institute. We need more tools to bridge the gap.

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Palamine, M.T, Armada, F., Jimenez, R. Locnen, SA. , Magsombol,EB., and Calleja, HB.

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  1. EXTRACORPOREAL SH0CKWAVE MYOCARDIAL REVASCULARIZATION IN PATIENTS WITH ISCHEMIC HEART DISEASE: THE ST. LUKE’S EXPERIENCE Palamine, M.T, Armada, F., Jimenez, R. Locnen, SA. , Magsombol,EB., and Calleja, HB. St. Luke’s Heart Institute

  2. We need more tools to bridge the gap. Wide Variability of Outcomes Pertaining to symptom relief among Interventional Studies Wijeysundera HC et al. Ann Intern Med. 2010;152:370-379.

  3. A New Option to Achieve Revascularization: ESMR Cardiospec System Components Shock Wave Applicator User Control Panel ECG Remote Control Unit Ultrasound Probe Holder ECG Monitor Treatment Table Shock Wave Power Unit Cabinet

  4. Collateral Development Post SW’s in Rabbits Nishida T, Shimokawa H et al. Circulation. 2004;110:3055-3061 Tohoku J Exp Med. 2008 Feb ;214 (2):151-8

  5. Background • This study documents our experience with ESMR in patients with known Coronary Artery Disease, Refractory Angina Pectoris and Ischemic Heart Failure.

  6. Methods Inclusion Criteria • CAD • Ischemic cardiomyopathy • Ischemic heart failure • Refractory angina • SPECT-documented reversible ischemia Exclusion criteria • Non ischemic cardiomyopathy • Decompensated heart failure • Intraventricular thrombus • Malignancy

  7. Methods

  8. Methods

  9. Results Table 1. Patient Demographics Table 2. Revascularization History The mean age was 65.89 +11.24 years.

  10. Table 4. ESMR Significantly improves symptoms Seattle Angina Questionnaire

  11. Table 5. SPECT Analysis and LDEDV Measurement

  12. Table 6. Wilcoxon Signed Ranks Test- SIZE AND SEVERITY OF ISCHEMIA

  13. 6 mos Post ESMR Pre ESMR

  14. Pre ESMR and Post ESMR

  15. Pre-ESMR 3 months Post-ESMR

  16. Results • All patients tolerated the treatment well. • No ECG changes, new wall motion abnormalities, and adverse events were reported.

  17. Conclusion • Our experience with ESMR showed promising results for patients with CAD, ischemic cardiomyopathy and ischemic heart failure patients with refractory angina. • ESMR improved symptoms, delayed the ischemic threshold and increased exercise tolerance and improved myocardial perfusion. • ESMR appeared safe and may improve symptoms which could lead to less hospitalizations.

  18. Thank you for your kind attention!

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