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Learn about atelectasis and bronchiectasis in animals. Explore the outbreak respiratory disease, laboratory findings, and clinical examinations. Discover the pathogenesis and differential diagnoses of effusions in cats and dogs.
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LAB 3 RESPIRATORY / QUIZ • Define the following terms: • Atelectasis • Bronchiectasis QUESTION 1
Slide 1 • Morphological Dx • Possible etiology:
Slide 2 • Morphological Dx • Possible etiology:
Slide 2 • Name the disease • Describe the pathogenesis:
Outbreak Respiratory Disease Several animals are sick or died with severe respiratory problems • Rule outs?
Bovine Respiratory Complex (BRD) • Enzootic pneumonia of calves: P. multocida, M. haemolytica, Mycoplasmas • Shipping Fever:M. haemolyica A1 • Viral respiratory infections: Parainfluenza-3 (PI-3 virus), Bovine Respiratory Syncytial Virus, Bovne Herpes Virus-1 (IBR), Bovine Viral Diarrhea (BVD)? • Atypical Interstitial Pneumonia: Bovine Pulmonary Edema dn Emphysema, Hypersensitivity Pneumonitis • Toxic gases
Laboratory Findings • Clinical examination: • Pyrexia 41C • Mucopurulent nasal discharge, moist cough • Increased bronchial sounds and crackles • Clinical pathology: • Leukocytosis with neutrophilia • Increased plasma fibrinogen • Presumptive diagnosis?
Two steers were sent for necropsy What would you expect to see grossly in the thoracic cavity?
Feedlot • What would be the texture of consolidated lung • What would you expect to see grossly on cut surface of the lung?
Feedlot • What would be the texture of consolidated lung • What would you expect to see grossly on cut surface of the lung?
Questions • What do you expect to see microscopically
Questions • Pathogenesis of the disease • Is prevention possible?
“Tiger” • 5-year-old DLH, intact, male cat • In the last four weeks the owner noticed: • Poor appetite • Weight loss • Not playing or exercising • Taken to the veterinarian • Thoracic pain on palpation • Dull sound on thoracic percussion • X rays showed: • obscure cardiac silhouette • poor pulmonary detail
“Tiger” • Ruled-outs: • What tests would your recommend? • Laboratory Results • CBC: Leukocytosis, neutrophilia • Thoracocenthesis:
This effusion is most likely: a.- Hydrothorax b.- Chylothorax c.- Pyothorax
“Tiger” The cat deteriorated in spite of treatment -Euthanasia • What would you see grossly ? • Do you expect extensive pulmonary involvement? • Pathogenesis? • What would expect to see microscopically
What would be the other differential diagnoses in a cat with effusion?: • Gross appearance of the effusion fluid • Gross lesions in postmortem examination • Biochemical analyses of the effusion • Cytological examination of the effusion
Chylothorax Cytology? Gross lesions on postmortem examination
2-year-old Rottweiler • Chronic cough • Exercise intolerance • Morphological Dx • Most likely etiology
What would you expect to see in the lungs? • Grossly • Microscopically
Diagnosis? Too Much Tequila