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TNT: New data on intensive lipid lowering in stable CHD patients

. TNT: Treating to New Targets. . LaRosa JC et al. N Engl J Med. 2005;352.. Hypothesis:Lowering LDL-C levels to well below 100 mg/dL could yield an incremental clinical benefitParticipants:10,001 patients with stable CHD and LDL-C 130-250 mg/dLTreatments:Atorvastatin 10 mg and 80 mgMedian

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TNT: New data on intensive lipid lowering in stable CHD patients

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    3. TNT: Treating to New Targets

    5. TNT: Design

    6. TNT: Baseline characteristics

    7. TNT: CV history of participants

    8. TNT: Baseline lipids

    9. TNT: Treatment effects on LDL-C

    10. TNT: Treatment effects on primary outcome

    11. TNT: Treatment effects on first major coronary event CHD death, MI, resuscitation after cardiac arrest

    12. TNT: Treatment effects on CHD death, MI

    13. TNT: Treatment effects on stroke

    14. TNT: Non-CV mortality

    15. TNT: Tolerability of treatments

    16. TNT: Extending and confirming benefit of LDL-C lowering beyond current guidelines

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