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Asbestos Exposure. Frans Naude. Asbestos Exposure. Inhalation of asbestos fibers. Asbestosis Def : diffuse interstitial pulmonary fibrosis that occurs secondary to the inhalation of asbestos fibers. Diagnostic imaging chest I 2-38 . Radiography. May be normal (10-20% )
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Asbestos Exposure Frans Naude
Asbestos Exposure • Inhalation of asbestos fibers
Asbestosis • Def : diffuse interstitial pulmonary fibrosis that occurs secondary to the inhalation of asbestos fibers
Radiography • May be normal (10-20%) • Peripheral lower zone predominance • Irregular reticular or small nodular opacities • "Shaggy" cardiac silhouette in advanced disease • Late: Endstage honeycombing • Pleural plaques (25%) • Lung cancer: Lower zone predominance in contrast to the upper zone predominance in the general population of smokers • Progressive massive fibrosis extremely rare
Small subpleural nodules (straight arrows), Patchy ground-glass opacities (curved arrows), Interlobular septalthickening (arrowhead) suggestive of early-stage asbestosis.
Pleural plaque : band like pleural thickening (arrowheads) in the lower lobe of both lungs
Asbestosis : subpleuralconsolidation (arrow) in the lower lobe of the left lung, with reticulation, ground-glassopacities, and honeycombing
Ptwith asbestos exposure: subpleural consolidation (arrow),pleural thickening (arrowheads) and effusion.
Subpleural Lines • curvilinear opacity a few millimeters or less in thickness, • less than 1 cm from the pleural surface • nonspecific indicator of atelectasis, fibrosis, or inflammation • more common in patients who have asbestosis than in those who have IPF or other causes of UIP
Asbestosis VS idiopathic pulmonaryfibrosis • IPF more basal and sub pleural fibrosis • presence of parietal pleural thickening in association with lung fibrosis is the most important feature differentiating asbestos- induced pulmonary fibrosis from IPF • asbestos bodies in bronchoalveolar lavage fluid
Case • H/O asbestos exposure
References • RadioGraphics 2006; 26:59–77 Pneumoconiosis: Comparison of Imaging and Pathologic Findings • Diagnostic imaging chest I 2-38 • High-Resolution CT of the Lung -webb