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mutations

mutations. Defined. Sometimes, mistakes are made while copying DNA. If those mistakes are not repaired, it leads to a… Mutation An error in DNA. 2 Kinds of Mutations. Point Mutation An error occurring at a single point in the DNA One base is changed to different base EX:

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mutations

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  1. mutations

  2. Defined • Sometimes, mistakes are made while copying DNA. If those mistakes are not repaired, it leads to a… • Mutation • An error in DNA

  3. 2 Kinds of Mutations • Point Mutation • An error occurring at a single point in the DNA • One base is changed to different base • EX: • Original strand: TAC GGA ATT CGC ATC CCC • Copied strand: TAC GGA ATT CTC ATC CCC

  4. 2 Kinds of Mutations • Frameshift Mutation • An error causing a shift in the DNA sequence • Addition of a new base or deletion of a base in DNA • EX: • Original: TAG CCT AAC ATG GCA TAT • Mutated: TAG CCT GAA CAT GGC ATA T • Original: TAG CCT AAC ATG GCA TAT • Mutated: TAG CCA ACA TGG CAT AT

  5. Results • A point mutation or a frameshift mutation can have a range of results on our proteins formed during protein synthesis… • Here’s how to classify the types of results:

  6. Results • Silent Mutation • The error in DNA causes no difference in the protein formed • Missense Mutation • The error in DNA causes a change in the protein formed, such as one incorrect amino acid • Nonsense Mutation • The error in DNA causes a MAJOR problem in the protein formed, such as the absence of a start codon, or an early stop codon

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