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WOUNDS-WOUND HEALING & CARE. Begashaw M . Layers of Skin. DEFINITION. Wound - break in normal continuity of a tissue cause - transfer of any form of energy. WOUND HEALING. is a complex biologic process of restoring normal tissue continuity
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WOUNDS-WOUND HEALING & CARE Begashaw M
DEFINITION • Wound - break in normal continuity of a tissue • cause - transfer ofany form of energy
WOUND HEALING • is a complex biologic process of restoring normal tissue continuity • integrated sequences of events leading to cellular proliferation and remodeling • starts immediately following the event of wounding
Phases of healing 1-Coagulation phase • first phase • is induced immediately following injury • characterized by vaso-constriction, clot formation and release of platelets
2- Inflammatory phase • takes place from time of wounding up to 3 days • Characterized: inflammatory response vasodilatation and pouring out of fluid migration ofinflammatory cells and leukocytes rapid epithelial growth
3- Proliferative Phase • phase of fibroplasia • starts around the 3rd day of injury • staysfor about 3 weeks • is characterized -fibroblast, epithelial and endothelial proliferation -Collagensynthesis &ground substance -blood vessel production
4- Maturation phase • phase of remodeling • takes the longest period - up to 1 yr • Equilibrium between protein synthesis and degradation occurs • with cross linking of collagen bundles leading to slow and continuous increase in tissuestrength
Clinical types of healing • Healing by first intention - clean wound closed primarily - healingby epithelialization - minimal scar - <6 hours, longer with facial • Healing by Second intention - in wide, contaminated wounds - not primarily closed - healing by granulation tissue formation - tissue contraction and epithelialization - inferior cosmetic result
Healing by third intention: -left open initially -closed later-delayed primary closure -In contaminated -long time lapse since initial injury -severe crush wound
Factors affecting healing • Local factors -Ischemia -decreased oxygen tension -foreign bodies -tension -Infection -Irradiation • Systemic factors -Systemic diseases-DM, cirrhosis, renal failure, malignancy -malnutrition -immunosupression -Drug- steroids, cytotoxic agents
WOUND ASSESSMENT AND CLASSIFICATION • Assessment History • Mechanism of injury • Time • Place and circumstance • past and current medical • immunization history
physical examination • Extent of skin loss • Degree of circulation • soft tissue injury • The degree of contamination • foreign body • tissue necrosis
Classification of wounds • Closed wound - an intact epithelial surface - skincover not completely breeched e.gContusion Bruise Hematoma • Open wounds - complete break of theepithelial protective surface E.g Abrasion Laceration Puncture Bites
Open wounds Tidy Untidy crushed Contaminated Devitalised tissue Often tissue loss • Incised • Clean • Healthy tissue • Seldom tissue loss
Classification of Surgical Wounds • Clean(no viscus opened) • Clean-contaminated(viscus opened minimal spillage) • Contaminated(open viscus with gross spillage or inflammatory ds) • Dirty(pus or perforation or incision via abscess)
WOUND MANAGEMENT -Priority: ABC -Stabilize-correct life threatening conditions • history & P/E -associated injuries • Assess wound • treatment • Follow up
Proper wound care: • stop bleeding • irrigation • debridement • decision -to close -leave the wound open • antibiotics • tetanus prophylaxis • correcting systemic disease
primary wound closure • Clean wounds • Clean-contaminated wounds -if they can be convertedinto clean wounds • all missile wounds, animal & human bites should never be primarily closed • in woundswithin 6-8 hours
Delayed primary closure • for traumatic or contaminated wounds • within 3 days
Secondary closure • wound left open to heal spontaneously • contraction (myofibroblasts) and granulation • requires dressing change • inferior cosmetic result • indication: when 1° closure not possible or indicated
Specific management • Bruises -Superficial -no specific management -localcompress -analgesics • Hematoma • collection of extravasated blood • Management: - absorbed spontaneously - Local compress to alleviate pain - aspiration-very large/ over a cosmetic area
Abrasion • is rubbing or scraping of skin or mucous membrane -variable depth • affect only a part orfull layer of skin • Management - Cleanse using scrubbing brushes - Use antiseptic or clean tap water and soap - Analgesic
Punctures • involve deeper structures • opening relatively small as compared with depth (e.g. needle) • Management: - Evaluate the depth - Remove - Excise damaged tissue - Cover with antibiotics - Tetanus prophylaxis
Lacerations • open wounds - knife, or glass • cut or torn tissue • Management: - cleansing - Closure - wound debridement - antibiotic - Tetanus Prophylaxis - Analgesics
Crush and avulsion wounds • complicated wounds • have more extensive damage • caused by compression • Management: - life threatening conditions - debridement • Early skin cover • late graft - wound left open if contaminated - antibiotics - Tetanus Prophylaxis - Analgesics
Missile injuries • compound , complicated • excessive tissuedamage • high degree of contamination • severe life threatening • Management - stabilize - debridement • Antibiotics • Tetanus Prophylaxis • analgesics - avoid primary closure
Human bites • heavily contaminated • due topolymicrobial-Staph> a-hemolytic Strep > Eikenellacorrodens >Bacteroides • Management - culture • Scrubbing • irrigation with saline - debridement - Leave wound open - Broad-spectrum antibiotic-augmentin - Tetanus Prophylaxis
Dog bites • can transmit the rabies virus • animal observation for 10 days • Local • irrigation and repeated swabbing • flushing -soap &water/antiseptics - anti-rabies serum infiltration - leave wound open • Systemic - Post exposure anti rabies prophylaxis (1ml, IM) on the 1st, 3rd, 7th, 14th and 28thday - Tetanus prophylaxis - Antibiotics
Snake Bites • First aid : - irrigation - pressure bandage proximally - Immobilize - Transport tohospital
Hospital Measures - Identify species - lab- hemoglobin, renal function - Anti-venom injection - Supportive care - Rest - IV-infusions to combat shock - Antibiotics - Blood transfusion - Tetanus Prophylaxis - Wound excision - Fasciotomy for compartment syndrome
WOUND COMPLICATIONS • Local - Hematoma - Seroma - Infection - Dehiscence - Granuloma - Scar - Contracture • systemic - shock -massive bleeding • bacteremia& sepsis • death