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SEMINAR ON BREAST CANCER AWARNESS. PRESENTED BY DR.RAMESH SAHARIA. SRIDHAR CANCER CARE CENTRE SRIMANTA SANKERDEV HOSPITAL. INCIDENCE AND PREVELANCE OF BREAST CANCER.
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SEMINAR ON BREAST CANCER AWARNESS PRESENTED BY DR.RAMESH SAHARIA. SRIDHAR CANCER CARE CENTRE SRIMANTA SANKERDEV HOSPITAL
INCIDENCE AND PREVELANCE OF BREAST CANCER. • Most common cancer in western & 2nd commonest cancer in India,after cervical cancer. • In metropolitan cities, it becomes commonest. • Incidence in India is 28/lac woman. • Incidence in West is 111/lac woman.
RISK FACTORS • Female. M:F 1:100 • Age at menarche. (<12yrs 2 fold+) • Age at menopause.(>55yrs 20%risk compare with <45 yrs) • Age at first live birth .(>30 yrs 2-5 fold+) • Breast feeding.(risk reduction per year of breast feeding is 4.3%) • Nulliparity. • Races/Ethnicity. • Family history/Number of 1st degree relatives with breast cancer.(1.5-3 fold, 5 times if B/L disease) • Current age.
continue:- • Number of previous benign breast biopsies. • Atypical hyperplasia.(4-5 fold) • Known or suspectedBRCA-1/2,p53(56-85% life-time risk of breast cancer) • Prior h/o chest radiation. • H/o current or prior HRT(25-35% excess risk) • Body mass index. • Breast density. • Alcohol consumption.(10-41%risk) • smoking
SYMPTOMS • Breast lump/mass • Chest /axilla lump. • Nipple discharge-blood,serous, pus, greenish. • Asymmetrical thickening/nodularity. • Nipple retraction or excoriation • Skin changes:-peaud’orange,ulcer,erythema, eczema. • Mets. Disease:-headache,breathing bone pain/fracture,abdominal lump ascites.
DIAGNOSIS • Clinical examination. • Mammography. • USG of breast & axilla. • FNAC. • Biopsy. • MRI breast • For mets:- CT brain, chest,abdoman. Bone scan. PET Scan.
.. NOW WHAT ? EARLY WE DIAGNOSED BETTER THE LIFE SMART WOMAN SEE “CAN” IN CANCER LET’S JOIN HANDS TO BEAT BREAST CANCER
BREAST SCREENING AND PREVENTION • Asymptomatic and –ve physical examination. NORMAL RISK. Age >/=20 but <40yrs • Clinical breast exam every 1-3yrs. • Periodic BSE. Age >/=40 yrs. • Annual clinical breast exam. • Annual mammography. • Periodic BSE.
Continue:- • INCREASED RISK. Prior thoracic RT Age <25yrs • Annual CBE. • Periodic BSE. Age >/=25yrs • Annual mammography + CBE 6-12 months. • Periodic BSE. LCIS/Atypical hyperplasia. • Annual mammography + CBE 6-12 months. • Periodic BSE • Consider risk reduction strategies.
Continue:- Strong family history or genetic predisposition. Age<25 yrs • Annual CBE. • Periodic BSE. Age >25 yrs • Annual mammography+CBE 6-12 months. • 5-10 yrs prior to youngest breast cancer cases. • Periodic BSE. • Annual MRI. • Consider risk reduction strategies.
Continue:- Prior history of breast cancer • CBE every 3 months for 1st yrs, every 6 months for next 2 yrs,then annually. • Annual mammography. • Monthly BSE. • Annual pap smear & pelvic exam. In woman on tamoxifen . • Bone scan, PET Scan.
RISK REDUCTION STRATEGIES • BRCA1/2,p53, PTEN gene mutation, strong family h/o breast & ovarian cancer, LCIS, thoracic radiation. • Bilateral breast removal +/-reconstruction.(90%decrease risk). • Bilateral ovary removal.(45-60%decrease risk.) • Risk reduction agents such as tamoxifen,raloxifene,anastrozole, letrozole.(35-40%)
CONCLUSION:- • Earlier we diagnosed breast CANCER better the prognosis & survival. • Delayed is due to lack of awareness, social embarrassment ,fear of procedure,or fear of cancer; woman may be reluctant to undergo screening. • Need of an hour to motivate woman to seek prevention services. • Awareness camp/seminar should be held. • Programs for new screening and treatment approaches.
INCIDENCE AND PREVELANCE OF CERVICAL CANCER. • Leading causes of cancer death world-wide. • 5 lacs new cases per year. • 3 lacs woman die anually. • Ranks no. one in India. • 1.3 lacs new cases anually in India. • 80-90%of cases occur among woman age 35 or elder,
RISK FACTORS:- • Human papilloma virus infection.(about 80% woman have,<5% develop cervical cancer, but all woman with cervical cancer had HPV). • Smoking. • Early age at first birth. • Use of hormonal contraceptives • Multi-parity. • Impaired immune system(HIV infection). • Multiple partners.
SYMPTOMS:- • Intermentrual bleeding. • Postmenopausal bleeding . • Postcoital bleeding. • Foul smelling discharge. • Pelvic/back pain. • Hematuria /rectal bleeding due to involvment of bladder /rectum.
DIAGNOSIS:- • PAP Smear • Colposcopy / visual inspection. • Biopsy . • USG/CTSCAN Abdomen. • Chest x-ray.
SCREENING AND PREVENTION OF CERVICAL CANCER. • Woman 30yrs or more. • PAP smear every1-3 yrs,if –ve ,can be done as & when required. • Visual inspection of cervix/Colposcopy (iodine/acetic acid stain,if abnormal, cryosurgery/biopsy.) • HPV detection. • Vaccination against HPV in adolscence & young girls. • Once in lifetime screening between 35-40yrs,reduces risk by 25-35%.Further screening at 5yrs intervals can reduces cancer risk.