1 / 9

Agenda

Agenda. Hearing Walking Facial strength Bowel/bladder function Pulmonary outcomes. Example of audiogram. Gardner-Robertson Hearing Classification Scheme. American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS). Hearing response criteria: 95% critical difference threshold.

elise
Download Presentation

Agenda

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Agenda • Hearing • Walking • Facial strength • Bowel/bladder function • Pulmonary outcomes

  2. Example of audiogram

  3. Gardner-Robertson Hearing Classification Scheme

  4. American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS)

  5. Hearing response criteria: 95% critical difference threshold Baseline score 95% critical difference threshold Floor effect Ceiling effect Rauch and Halpin, 2006

  6. House-Brackman facial weakness

  7. Semi-automated software

  8. Walking (from approval of ampyra) • Inclusion criteria included the ability to walk 25 feet in 8–45 seconds • The primary measure of efficacy in both trials was walking speed (in feet per second) as measured by the Timed 25-foot Walk (T25W), using a responder analysis. • A responder was defined as a patient who showed faster walking speed for a least three visits out of a possible four during the double-blind period than the maximum value achieved in the five non-double-blind no treatment visits (four before the double-blind period and one after).

  9. Other endpoints • Walking • Bowel/bladder function • Respiratory function

More Related