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ASSALAMU’ALAIKUM WR.WB.

ASSALAMU’ALAIKUM WR.WB. Tiada sia-sia Meraih Ilmu dan Mengamalkannya. Tambahkanlah Ilmuku dan Berilah aku pengertian dengan baik. DIURETIK. DASAR PENGGUNAAN : PENINGKATAN TEKANAN INTRA OKULER / GLAUKOMA HIPOPROTEINEMIA HEART FAILLUR TRAUMATIC RENAL FAILLUR

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ASSALAMU’ALAIKUM WR.WB.

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  1. ASSALAMU’ALAIKUM WR.WB. Tiadasia-sia MeraihIlmudanMengamalkannya TambahkanlahIlmukudan Berilahakupengertiandenganbaik

  2. DIURETIK

  3. DASAR PENGGUNAAN : • PENINGKATAN TEKANAN INTRA OKULER / GLAUKOMA • HIPOPROTEINEMIA • HEART FAILLUR • TRAUMATIC • RENAL FAILLUR • TOXIN EXCRETION • DRUG OVER DOSE • HYPERTENSI • OEDEMA PULMONUM • CALCIURIA

  4. Mechanism of action: Inhibits Na+ & Cl- reabsorption in the loop of Henle & proximal & distal tubules of nephron: *markedly increases excretion of Cl-, Na+, & water *also increases excretion of K+, Mg++, Ca++, ammonium, H+, bicarbonate, & phosphate Side Effects/Adverse Effects: Dose-related hypokalemia, dehydration, postural hypotension, hypochloremic alkalosis, azotemia

  5. Mechanism of action: Interferes with reabsorption of Na+ & Cl- in the distal convoluted tubule of the nephron, thus: *increases Na+ excretion, causing increased urine output *also increases excretion of K+, Mg++, Ca++, ammonium, H+, bicarbonate, & phosphate *decreases calcium & uric acid excretion Side Effects: Frequent - hypokalemia, dizziness, muscle weakness, dry mouth, thirst, Interactions: the same as Lasix, due to effects on lytes

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