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Abnormal BDNF Signaling in Autism. * * p <0.01 * p <0.05. p<0.01. p<0.05. BDNF. TrkB. TrkB. p<0.05. PI3K. E3b1. Akt. Eps8. Sos-1. Rac. p<0.01. mTOR. ( Wayman et al., 2008 ). Changes in spine dynamics and stability. p<0.05. Changes in spine protein translation. S6 Kinase.
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Abnormal BDNF Signaling in Autism * * p<0.01 * p<0.05 p<0.01 p<0.05 BDNF TrkB TrkB p<0.05 PI3K E3b1 Akt Eps8 Sos-1 Rac p<0.01 mTOR (Wayman et al., 2008) Changes in spine dynamics and stability p<0.05 Changes in spine protein translation S6 Kinase