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National DNA Kinship Project for Missing Persons and DVI. NCIDD. Stores and matches DNA profiles under different categories including: Missing Persons Unknown Deceased Volunteer (Limited Purpose). National Usage. February 2007. National Usage. November 2007. Database = 350,000.
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National DNA Kinship Project for Missing Persons and DVI
NCIDD Stores and matches DNA profiles under different categories including: • Missing Persons • Unknown Deceased • Volunteer (Limited Purpose)
National Usage February 2007
National Usage November 2007 Database = 350,000
Why Use DNA? • A number of human remains cannot be identifiedvisually, with fingerprint or dental examination. • Often there are no clues to the identity of the remains. • Such unidentified remains may only be resolved using DNA.
The Three Critical Elements • Reference DNA • Post-Mortem DNA (Unknown Deceased) • Database searching and matching
Identification Triangle Post-Mortem DNA Reference DNA Database Searching and Matching
Reference DNA Direct References • Personal Effects • Medical Samples Kinship References • Close relatives
Direct Reference DNA Missing Person 11,14 18,19 28,28 16,18 9,11 15,15 17,19 13,13 18,18 Unknown Deceased 11,14 18,19 28,28 16,18 9,11 15,15 17,19 13,13 18,18
Kinship matching FatherMother 14 1516 17 Sibling 2 15 17 Missing Child Sibling 1 14 17 14 16
Project Board Executive David Lang (Manager IST) Senior Users Leonie Jacques (AFP) Laszlo Szabo (BSAG) Scott Tilyard (TasPol) Senior Supplier Kirsty Wright Kinship Matching Project “On behalf of our family, we need to know what happened to him.”
Investigation by Police Coroner’s Orders Autopsy Dental Examination DNA Investigation by Police Coroner’s Findings
Operation Bravo Jute & Skeletal Remains Project Successes Queensland Police, Queensland Health and the Office of the State Coroner
Queensland Missing PersonsDNA Database Identification 1 (Missing 14 years) • Remains found partially buried in a field in 1992 • A 12 loci DNA profile was obtained from the remains in 2004 • In 2004 the remains were matched to a man that went missing in 1990, using his daughter’s DNA sample
Queensland Missing PersonsDNA Database Identification 2 (Missing 7 years) • Remains found on a rock surface in bushland in 2004 • A 9 loci DNA profile was obtained from the remains in 2005 • The remains were matched with a teenage boy that went missing in 1998, using his parent’s DNA samples
Queensland Missing PersonsDNA Database Identification 3 (Missing 9 years) • Remains found in bushland in 2003 • In 2004 nDNA profiling and mtDNA profiling failed • An eight loci nDNA profile was obtained in 2006 • The remains matched to a man that went missing in 1996, using his mother’s and sister’s DNA samples • The ID of the remains has assisted the homicide investigation