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Team IMAC Integrative Medicine and Cancer

Team IMAC Integrative Medicine and Cancer. Krupa Nataraj Jessica Nooralian Mihir Patel Jessica Stevens Vivian Wang Albert Zhou. Peter Frechette Stephanie Galanie Kevin Gu Anna Hung Sarah Kim Kelsey Merrick. Mentor: Dr. Mark Kantor. Introduction . Cancer – a leading cause of death

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Team IMAC Integrative Medicine and Cancer

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  1. Team IMACIntegrative Medicine and Cancer Krupa Nataraj Jessica Nooralian Mihir Patel Jessica Stevens Vivian Wang Albert Zhou Peter Frechette Stephanie Galanie Kevin Gu Anna Hung Sarah Kim Kelsey Merrick Mentor: Dr. Mark Kantor

  2. Introduction • Cancer – a leading cause of death • Complementary and Alternative Medicine (CAM) • Many patients seek alternative treatments • CAM is still largely unexplored http://www.fda.gov/consumer/updates/pics/doctor_patient.jpg

  3. Literature Review • The use of CAM • Ingestible herbal supplements • Reasons for CAM use search.ugent.be/libtiger/img/books.jpg

  4. Objective • To investigate the use and perceptions of herbal dietary supplements among a group of female breast cancer survivors and test the effects and safety of the most commonly used herbal dietary supplements.

  5. Methodology (Mixed-Method Design) • Questionnaire (descriptive, quantitative/qualitative) • Laboratory work (experimental, quantitative) https://decs.nhgl.med.navy.mil/SURVEY/survey.gif http://www.chemlabs.bris.ac.uk/cetlpics/Outreach/Chemnet_NAGTY06labbig.jpg

  6. Survey Purpose • To understand patients’ uses/perceptions of herbal dietary supplements • Most commonly used • Frequency • Perceived efficacy/safety • Reasons for use • Sources of information

  7. Questionnaire - Example

  8. Sampling Frame Options • George Washington University Medical Center • Paper survey • Georgetown University • Paper survey • BreastCancer.Net News • Online survey http://www.gwu.edu/~resobgyn/circle.gif

  9. Survey Analysis • Frequency and statistical correlation • Limitations • Sampling error • Response error • Non-response error http://www.xycoon.com/images/freque1.jpg

  10. Lab Work • Dr. Tom Wang • Agricultural Research Service; Diet, Genetics, and Immunology (USDA) • Effects – Proliferation and Cell Cycle • Dr. Tom Flynn • Center for Food Safety and Applied Nutrition; Department of Toxicology (FDA) • Safety – Liver Toxicity

  11. Conclusion • Objective • Investigate the use and perceptions of herbal dietary supplements of female breast cancer survivors and test the effects and safety of the most commonly used herbal dietary supplements • Publication in scholarly journal • Contribution to literature http://infocusmagazine.org/5.1/images/hs_cam_standards.jpg

  12. Spring 2008 Fall 2008 Spring 2009 • Thesis proposal • Obtain IRB approval • Develop and pilot survey • Design laboratory experiments • Create team website • Administer surveys • Outline thesis • Draft literature review for thesis • Fall colloquia • Begin lab research • Finish survey data collection • Organize survey data • Draft chapters 1, 2, and 3 of thesis • Undergraduate Research Day • Continue lab research Timeline (I)

  13. Fall 2009 Spring 2010 • Complete survey data analysis • Draft chapters 4 and 5 • Draft presentation for thesis conference • Five experts for conference panel • Finish lab data collection and analysis • Submit final team information • Finish thesis • Thesis conference • Submit final thesis for publication Timeline (II)

  14. Budget • Surveying costs • Online advertisement or printing • Statistician consultation fees • Laboratory costs • Supplements • Cell line media • Future conferences www.rig.netfirms.com

  15. Acknowledgements • Dr. Kantor, Team Mentor • Dr. Tom Wang • Dr. Tom Flynn • Dr. Gordon Willis • Dr. James Wallace • Dr. Rebecca Thomas • Courtenay Barrett

  16. Thank You. Questions?

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