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Cardiac Modeling of Steady-State Transients in the Ventricular Myocyte

Cardiac Modeling of Steady-State Transients in the Ventricular Myocyte. Raymond Tran University of Queensland July 10 2013 UCSD PRIME. Progress. Learned to run experiments on Nimrod Portal. Executed basic test runs on single parameters adjustments with Nimrod/G.

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Cardiac Modeling of Steady-State Transients in the Ventricular Myocyte

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  1. Cardiac Modeling of Steady-State Transients in the Ventricular Myocyte Raymond Tran University of Queensland July 10 2013 UCSD PRIME

  2. Progress • Learned to run experiments on Nimrod Portal. • Executed basic test runs on single parameters adjustments with Nimrod/G. • Adjusted MATLAB code and Nimrod plan file in preparation for parametric sweep of applied current values.

  3. Current Objectives • Need to write a MATLAB script for the plan file that extracts the values of AP, [Ca]i, [Na]i, and [K]i and plots their change over time to reduce amount of memory transferred on Nimrod. The current plan file of the experiment that needs to be adjusted.

  4. Goals • Begin first experiment by testing a range of values for the applied current. • After testing the applied current, I will test a combination of values for the applied current with its duration.

  5. Culture

  6. Acknowledgements University of California, San Diego • Dr. Anushka Michailova, Department of Bioengineering. • UCSD PRIME – Dr. Peter Arzberger, Dr. Gabriele Wienhausen, Ms. Teri Simas. University of Queensland • Dr. David Abramson, Centre for Research Computing • Hoang Nguyen, Ph.D. student at University of Queensland

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