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Taenia solium. Ashley Tharayil 11/27/2006. Review. “Pork tapeworm” Transmitted by eating undercooked pork. Review. 2 .) taeniasis – digestive tract Develops when adult tapeworm infects human intestine 3-6 feet long Asymptomatic but continuous source of eggs in the feces.
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Taenia solium Ashley Tharayil 11/27/2006
Review • “Pork tapeworm” • Transmitted by eating undercooked pork
Review • 2.) taeniasis – digestive tract • Develops when adult tapeworm infects human intestine • 3-6 feet long • Asymptomatic but continuous source of eggs in the feces 1.) cysticerosis – muscle tissues • Eggs cross digestive tract, enter circulation, and lodge in muscle tissues • If it’s in the brain it’s neurocysticerosis
DISCOVERY • Worms, in general, mentioned in pre-renaissance text. • Linnaeus identified and named T.solium
HISTORICAL ACCOUNTS • De Taenia Humana (Plitz) and Taenia media-canellata, offer insights about T. solium.(info on where and how the worm lives)
George Kennedy Frink • Hippocrates was the first person to identify T. Solium. • another ancient Greek, Pallas, the first to discover that parasites ("entezoa") "sprung from similar parents"
What effect do cultural practices have on the Pork tapeworm? Diet!! eating Pork increases prevalence(if poor sanitation) Not eating pork decreases prevalence • Very little prevalence in Islamic/Judaic countries
Prevalence • T. solium are high in Mexico, Central and South America, Africa, Asia, Spain, and Portugal. • Countries where people like to eat their meat undercooked (like some parts of Europe and Asia) have high infection rates
EFFECT OF MIGRATIONS • Very rare in the U.S. • Only cases are from immigrants/travelers • Same in Islamic countries
Practices that can increase prevalence • Extensive or free range pig rearing • Outdoor human defecation near/in pig rearing areas • Use of pigs as “sanitary policemen” • “Pig style privies” • Using night soil… and the OBVIOUS.. • Eating undercooked pork
Treatment? • Cysticercosis outside the central nervous system is treated surgically • niclosamide • praziquantel • albendazole
Niclosamide • Niclosamide is used to specifically treat tapeworms • Chewable tablet • Side effects: • abdominal pain, anorexia, diarrhea, and emesis. Rarely, dizziness, skin rash, drowsiness, and an unpleasant taste
Praziquantel • the permeability of the membranes of parasite cells. The drug thereby induces contraction of the parasites resulting in paralysis in the contracted state • Side effects: abdominal pain, drowsiness, headache, dizziness, fatigue, diarrhea,sweating, fever, arthalgia, etc.
Albendazole • Drug indicated for the treatment of a variety of worm infestations • Side effects: birth defects, liver problems, in eye patients treated for neurocysticercosis can cause eye lesions
Work Cited • http://www.stanford.edu/class/humbio103/ParaSites2001/taeniasis/solium2.html#epidemiology • http://www.stanford.edu/class/humbio103/ParaSites2006/Taenia_solium/History%20of%20Discovery.html • http://www.path.cam.ac.uk/~schisto/Tapes/Taenia.html • www.cdc.gov/taeniasolium • http://www.medterms.com/script/main/art.asp?articlekey=5706 • http://medinfo.ufl.edu/year2/mmid/bms5300/bugs/taensoli.html
Who first identified T.solium? • Carl Linnaeus • Name two 19th C.E. books that synthesized info on T.solium? • De Taenia Humana (Plitz) and Taenia media-canellata • Name 4 countries where T.solium is most prevalent • Mexico, Central and South America, Africa, Asia, Spain, and Portugal.
What was the Bible reading? • Levit.11 • Name the three drugs used for treatment Niclosamide, praziquantel ,albendazole