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Malattia di Parkinson. Diagnosi differenziale. Cholinergic and adrenergic nerves. Autonomic reflex pathways. Innervation of the heart. Autonomic nerves and ganglia in the pelvis. Malattia di Parkinson. Genetica. Loci and genes linked to familial PD. The Marsala kindred.
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Malattia di Parkinson Diagnosi differenziale
Cholinergic and adrenergic nerves Autonomic reflex pathways
Innervation of the heart Autonomic nerves and ganglia in the pelvis
Malattia di Parkinson Genetica
Malattia di Parkinson Neurostimolazione
Methods • Surgical procedure • Surgery performed in the practically defined off condition • Talairach’s stereotactic frame modified for a polar approach. Ventriculography • Bilateral implant of a Medtronic 3389 lead 3389 Moro et al. 1999
Bilateral STN implant LEDD reduction at 24 months: -62.9% Romito et al. 2002
Bilateral STN implant Romito et a. 2002
Bilateral STN implant Romito et a. 2002
Distonia Neurostimolazione
a b c d A patient with generalized dystonia and prominent axial involvement is shown before (a, b) and 6 months after implant with high frequency stimulation implant in the GPi (c, d). The improvement in posture and gait is evident from these still frames taken from video clips (courtesy of Dr. Nardocci).