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Discover the best brain stimulation treatments for mental illnesses like Major Depressive Disorder and Parkinson’s Disease. Explore different therapies such as Electrocompulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Deep Brain Stimulation (DBS), and the innovative TREMTEX STIMband. Compare effectiveness, side effects, and promising outcomes in this comprehensive guide.
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Best Brain Stimulation Treatment for Mental Illnesses By Liam Phelan
The Problem • Major Depressive Disorder: MDD effects approximately 9.9million American adults. • If not properly treated it can become treatment-resistant depression. • There are estimated 7-10million people world wide who suffer from Parkinson’s Disease. • There are 60,000 Americans diagnosed each year with Parkinson’s. http://www.miraresearch.org/understanding/statistics/ http://www.pdf.org/en/parkinson_statistics
Brain Stimulation THERAPIES • There are three main types of brain stimulation therapies: • Electrocompulsive Therapy (ECT) • Transcranial Magnetic Stimulation (TMS) • Deep Brain Stimulation (DBS) • A subfield of this is transcranial Direct Current Stimulation (tDCS)
ElectroCompulsive Therapy (ECT) • Side Effects • Headache • Muscle ache • Upset stomach • Short termmemory issues • Used to treat depression • Can use one diode (unilateral) or two diodes (bilateral) which are placed on scalp in target areas. • Patients are put under with anesthia and given a muscle relaxer • Patients are shocked for around a minute. • Multiple sessions needed to treat http://www.nimh.nih.gov/health/topics/brain-stimulation-therapies/brain-stimulation-therapies.shtml#Fitzgerald
Transcranial Magnetic Stimulation (TMS) • Used to treat depression • Electromagnet placed over target area • Stimulus sent to electromagnet in pulses • Treatment lasts ~40 minutes • Only a few sessions needed • Side Effects • Headache • Muscle contractions in face and jaw • discomfort • Lightheadedness http://www.nimh.nih.gov/health/topics/brain-stimulation-therapies/brain-stimulation-therapies.shtml#Fitzgerald
Deep Brain Stimulation (DBS) • Used to treat Parkinson’s and most recently used in depression trials • Two electrodes implanted in brain(generally at motor cortexes) • Pulse generator implanted in chest, sends constant pulse to electrodes • Side Effects • Surgical liabilities • Unwanted moodchanges • Movement disorders • Lightheadedness • Trouble sleeping http://www.nimh.nih.gov/health/topics/brain-stimulation-therapies/brain-stimulation-therapies.shtml#Fitzgerald
TREMTEX STIMband • Used to treat Parkinson’s disease • Uses transcranial Direct Current Stimulation • Electrodes placed over motor cortexes • Used in 20 minute periods daily • Stimband not tested on humans yet, tDCS however has been • Side Effects of tDCS • Headache • Lightheadedness • Nausea https://en.wikipedia.org/wiki/Transcranial_direct-current_stimulation#Side_effects_of_stimulation http://www.bme.jhu.edu/news-events/news-highlights.php?id=510 http://www.baltimoresun.com/health/maryland-health/bs-hs-parkinsons-device-20150716-story.html http://hub.jhu.edu/2015/06/10/stimband-brain-stimulator
ECT DATA http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3905244/
TMS DATA http://archpsyc.jamanetwork.com/article.aspx?articleid=207938
DBS DATA http://www.sciencedirect.com/science/article/pii/S089662730500156X
Stimband data https://youtu.be/vrpVYfQaevw?t=2m59s
Results and comparison • ECT is still very effective, probably the best option for what it can treat. • TMS has little to no effect on individuals suffering from depression. • Use of DBS for Parkinson’s is costly and ineffective • However, it use to cure MDD is very promising • The stimband and use of tDCS is very promising towards the control of Parkinson’s symptoms, and is the best Brain Stimulation treatment for that neu