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fMRI: Biological Basis and Experiment Design Lecture 24: GLM in all its glory. Previously. Assumed shape of HIRF, analysis for single voxel. =. X. time. Previously. voxels. Assumed shape of HIRF, analysis in many voxels. X. =. time. voxels. Today.
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fMRI: Biological Basis and Experiment DesignLecture 24: GLM in all its glory
Previously ... Assumed shape of HIRF, analysis for single voxel = X time
Previously ... voxels Assumed shape of HIRF, analysis in many voxels X = time voxels
Today Estimate shape of HIRF (single voxel) x = time
Design matrix Assuming HIRF: Not assuming HIRF: stim 1 stim 2 stim 3 baseline trends, etc. stim 1 stim 2 stim 3 time
Regression coefficients Assuming HIRF: Not assuming HIRF: stim 1 stim 1 stim 2 stim 3 stim 2 trend 1 trend 2 stim 3 trend 3 trends
Example 1: Slow ER, "same" HIRFs, no trends A x no trends Data simulation: A*x + noise