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Functional Genomics. … to …. Evolution of biomedical innovation potential …. 1970s 1975 1980 1985 1990 1992 1994 1995 199 6 199 7 199 8 199 9 2000 2001 200 2 200 4 200 6. Functional Genetics. From ….
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Functional Genomics …to … Evolution of biomedical innovation potential … 1970s1975 198019851990199219941995 1996 1997 1998 199920002001 2002 2004 2006 Functional Genetics From…
An Integrative Approach for Discovery of Gene Function in Immunological Disease Gene & pathway validation in animal models New Animal Models Gene & pathway prediction Functional Genetics Cross platform validation (GO, QTLs, human) Molecular & Cellular pathways Sensitized ENU mutagenesis Expression profiling
New knowledge & Innovation Business Research € €€€
The Greek perspective; Can we succeed in a new knowledge-driven economy? • Excellent Greek scientists exist all over the world (including Greece) • EU membership • Small country providing advantages on focus and synergies
… on research • Biomedical Research highly fragmented • National Policies and Instruments still pending • Industrial collaborations without impact • Nuclei of excellence still exist • Reforms and investment necessary
A few Recommendations for an Integrated Support of the Greek Research Environment • Reform National Research Funding System (involve stakeholders) • Meritocracy and accountability – follow international standards • Integrated design based on excellence and first-rate scientists • Foster creative research careers of outstanding young researchers • Develop large infrastructures / projects needed for innovation • Invest more on Research Institutes (rather than Universities) • Incubate technology transfer structures with free academic research
… on commercialization • Lack of entepreneurship and business skills • Little help for start-ups • (IPR management, financing, management) • Limited access to knowledge portfolios • Need for a common vision between R&B • Reforms and investment necessary
A few Recommendations for an Integrated Support of the Greek Innovative Business Environment • Business start-up incentives and assistance or mentoring • IPR assistance and management for Biotech • High standards incubating facilities / clusters • Financing and further organizational support • Support for further R&D in start-ups • Integrated National Innovation System
Research Institutes Mouse Clinic Technology Incubator (Vari – Greece) BIOMEDICAL SCIENCES RESEARCH CENTRE ‘ALEXANDER FLEMING’ A European Centre of Excellence in Functional Genomics