Skin Care

1. Skin Care

2. skin • The skin is the largest organ of the body • The skin protects us from microbes • Helps regulate Body temperature • Permits the Sensation of touch, heat and cold. • Separates and protects the internal environment from the external one.

3. Skin performs the following functions: • Protection • Sensation • Thermoregulation • Control of evaporation • Absorption

4. Skin function

5. Skin Type • Skin types vary depending upon factors such as: • Water content, which affects your skin's comfort and elasticity • Oil (lipid) content, which affects your skin's softness • Sensitivity level Normal Skin Oily Skin Dry Skin Sensitive Skin Combination Skin

6. FACTORS AFFECTING SKIN PENETRATION Age Skin condition Hydration of the skin

7. Skin Problems • Acne • Sunburn • Dark under eye Circles • Wrinkles • Hyperpigmentation

8. Effect of Pollution on Skin • Pollution is one of the main sources of damage to the skin. • Free radicals interfere with the skin’s ability to produce collagen. • Contaminants makes skin dry, wrinkled, and clogged.

9. Effect of Smoking on Skin • Tobacco and other related chemicals are regarded as skin aging accelerators  causes of aging skin.  • Smoking has adverse effects on our nerve endings which can cause sensitivity and dryness. • This results in dehydration. Eventually, this can be one of the most commonwrinkle causes.

10. Effect of Drinking on Skin • Alcohol dehydrates the skin. It will slowly lose firmness, plumpness. • Alcohol consumption leads to the opening of our blood vessels which makes the face puffier and causes dark circles under the eyes.

11. Have you ever thought to what extent the foods you eat can affect your skin? • Junk food is related to various chronic skin issues. • Certain foods consumed in excess and on a longer period of time can have negative effects upon our skin causing acne, wrinkles • Sugar • Salty Food • Fats • Dairy Products • Sodas and Caffeine • Alcohol

12. Skin Care Products

13. Sami Direct introduces the “FACE WASH CREAM” which essentially helps improve skin complexion, and nourishes the skin to make it bright and radiant.

14. Key benefits

15. Ingredients for Face Wash

16. Supporting Studies • Soy Isoflavones • Soy Isoflavones are obtained from the seeds of Glycine max. The product is standardized to contain 50% total isoflavones (25% genistein and 25% diadzein). • Topical application of soy isoflavones help counter some of the negative age-related changes like decrease of skin thickness, dryness and loss of elasticity. It is known as a tyrosine kinase inhibitor and the slightly estrogenic active, genistein, the bioactive form of the predominant soy isoflavones, has the potential to stimulate collagen in the skin. Thus soy isoflavones efficiently reduce lines and wrinkles, redensify and firm the skin. • Lemon Peel Extract PG • Lemon Peel Extract is a rich source of flavonoid glycosides, coumarins, sitosterol, glycosides and volatile oils. Citrus flavonoids have a strong antimicrobial activity. It is reported that in certain skin flora like Pseudomonas and Micrococcus can grow in presence of sebum, especially when it is secreted in excess, and cause purulent skin infections. • Papaya Extract • Papaya contains an important enzyme called papain that helps in natural renewal of skin and also is also is known to help in skin whitening. In addition, papaya is rich in important nutrients and vitamins that together help your skin remain clear, spot free and naturally soft, supple and beautiful.

17. Turmeric oil: • Turmeric oil contains ar-turmerone, β-turmerone and ß- turmerone. It possesses antioxidant, anti-inflammatory and antimicrobial properties. It is reported that ar-turmerone inhibits melanin synthesis by blocking the tyrosinase enzyme. • 1, 2-Decanediol and1,2-Octanediol: • 1, 2-Diols (1, 2-Decanediol and 1, 2-Octanediol) posses moisturising property and also hold anti-microbial properties, can therefore help reduce the amount of preservative required in a formulation. • Vitamin E Acetate • Vitamin E Acetate is the stable form of Vitamin E most often used in cosmetic formulations. Vitamin E protects cell membranes from damage by oxygen free radicals. It can prevent premature aging of the skin induced by UV irradiation and lipid peroxidation. • Vitamin E acetate is converted to its biologically active form, vitamin E, within the skin when applied topically. Studies have shown that topical use of tocopherol and alpha tocopheryl acetate are more effective than dietary supplementation in increasing the vitamin E content of the skin.

18. Fairness Cream "Fairness Cream", with multiple UV benefits, is a light non-greasy cream, with a unique blend of melanin suppressors, helps to lighten the skin tone, eliminate pigmentation problems naturally.

19. KEY BENEFITS 1 • Visibly lightens complexion. 2 • Helps lighten / remove blemish, freckles and acne marks. 3 Helps visibly lighten the hyper pigmentation in the skin 4 Protects skin against harmful UV radiation Significantly improves skin elasticity

20. INGREDIENTS *Trademark of Sabinsa Corporation

21. SabiWhite® - Good Anti-Oxidant Greater the ORAC value, better is the Antioxidant potential 21

22. Anti-ageing potential of OlePent® Collagenase activity Elastase activity Loss in skin elasticity Loss in skin Tone & structure Sagging, Wrinkling, stress induced pigmentation Spider veins And premature ageing Damage of skin dermis Inflammation Increases TGF-β Rebuilds collagen Inflammatory mediators Free radicals TGF-beta activity

23. OlePent ®does: UP TO 80% Elastase inhibitionIncreaseselasticity Collagenase inhibitionRepairs wrinkles TGF beta increaseRebuilds Collagen Anti oxidantGives skin a more luminous, uniform complexion UP TO 86% UP TO 90% UP TO 30%

24. OlePent ® REPAIRING PEPTIDE FIRMING PEPTIDE • This peptide stimulates the skin’s natural production of collagen • Restores the structure of the skin and smooth wrinkles. • Minimizes the effect of degrading enzyme • This peptide has anti-inflammatory properties • Helps in repairing skin barrier dysfunction • Repairs skin injury caused by either wound or photo damage.

25. Supporting Studies • Licorice extract 40% CA • Licorice extract 40% CA is a standardized extract from the dried roots of Glycyrrhizaglabra and it contains a minimum of 40% Glabridin. Glabridin is a potential molecule which is known for its skin lightening properties. Licorice possesses potent and effective anti-inflammatory, antioxidant as well as melanogenesis-inhibiting properties. • SabiWhite® • SabiWhite® is a color-free natural extract derived from Curcuma longa (Turmeric) rhizomes. • SabiWhite® offers effective topical antioxidant protection. Its antioxidant action is of a comprehensive "bioprotectant" nature, efficiently preventing the formation of free radicals, while quenching pre-formed ones as well. This dual action protects the skin cells from damage by UV radiation and the resultant inflammation and injury with far reaching beneficial effects on overall health and well being. • In vitro studies indicate that SabiWhite® efficiently inhibits tyrosinase, the rate limiting enzyme in the synthesis of melanin. Its efficacy is superior to that of commonly used natural skin lightening agents such as Kojic acid, and of related compounds.

26. pTeroWhite® • pTeroWhite® is a standardized extract from the dried heart wood of Pterocarpusmarsupium and contains a minimum of 90% PteroStilbene. Pterostilbene, a structural analog of resveratrol, is more stable in vivo than resveratrol. • pTeroWhite® offers antioxidant, anti-inflammatory support and lightens skin tone. • OLEPENT® • OLEPENT®, is a novel, patent pending, unique pentapeptide developed by Sami - Sabinsa group. • Natural peptides are needed to regenerate collagen continuously. Peptides also help in plumping up the skin cells. OLEPENT®, enhances dermal matrix regenerating activity. This provides a synergistic activity by reducing the appearance of fine expression lines and wrinkles. The triterpenoid group acts by preventing oxidation and excess activity of serine proteases like elastase and collagenase that result in the wrinkling of skin. With added peptides which boost collagen and other dermal matrix protein, the triterpenoid provides complete protection against wrinkles. • Cosmoperine • Cosmoperine is a dermal penetration enhancer. It is standardized for 98.5% Tetrahydropiperine and is prepared from Piper nigrum (Pepper) by a proprietary process. It is used as a skin permeation enhancer for other active ingredients in formulations.

27. “Moisturizing Cream” from Sami Direct is a light cream that helps to replenish the skin’s moisture reserves the natural way and also provides nourishment to optimize skin renewal.

28. Key Benefits of Moisturizing Cream • Intensive hydration and rejuvenation of the skin. • Provides nutrition and maintain skin balance. • Promotes cell renewal and restores skin vitality. • Minimize Trans-epidermal water loss.

29. Moisturizing Cream Formula

30. Supporting Studies • Cococin™ WS • Cococin™ WS is obtained from tender coconut water (Cocosnucifera), is a white free flowing powder and soluble in water. Coconut water is the nutrient-rich liquid endosperm of coconut abounding in proteins, amino acids, sugars, vitamins, minerals and growth hormones that support healthy cell growth & hydration. • Amaranthus SCFE • Amaranthus SCFE is a standardized extract from the seeds of Amaranthuscaudatus and contains a minimum of 5% Squalene. Squalene is quickly and efficiently absorbed deep into the skin, restoring healthy suppleness and flexibility without leaving an oily residue. • Squalene functions in the skin as a quencher of singlet oxygen, protecting human skin surfaces from lipid peroxidation due to exposure to UV light and other sources of oxidative damage. • Sesame Oil • Sesame Oil, obtained from the seeds of Sesamumindicum, is traditionally recognized in India for its nourishing and moisturizing properties. It helps prevent the skin from getting excessively dry. Sesame oil helps to soften, hydrate and rejuvenate the skin.

31. Jojoba Oil • Jojoba oil is the liquid waxy material produced in the seeds of the plant Simmondsiachinensis and is a mix of wax esters. It helps provide elasticity and renders smoothness to the skin. Jojoba oil offers lubrication to the skin, retards water loss and enhances flexibility and suppleness of the skin. • Shea Butter • Shea Butter is a natural fat extracted from the nut of the shea tree. It is widely used in cosmetics as a moisturizer and emollient. • Shea butter contains fatty acids which help to retain skin moisture and elasticity, hence acts as an effective moisturizer. It also helps to diminish wrinkles by moisturizing the skin, promoting cell renewal, and increasing circulation. • Kokum Butter • Kokum butter is a solid fat obtained from the seeds of the Garciniaindica tree. Kokum butter is rich in the antioxidant vitamin E, which is excellent for the skin. It helps to regenerate skin cells, also supports skin elasticity and general flexibility.

32. Under eye Cream Sami Direct introduces the “UNDER EYE CREAM” which essentially helps revive, improve and provide an all-round treatment for problems experienced in the skin around the eyes.

33. Key Benefits • Helps to reduce the dark circles • Helps to reduce puffy eyebags • Helps to reduce wrinkles to the eye area • Helps stimulate skin cell growth • Helps proper micro circulation of blood to the eye area • Helps reduce crow’s feet and puffiness • Helps to restore and protects the natural eye contour • Helps to refines the skin • Helps to remove the fine lines

34. Ingredients of Under Eye Cream

35. Supporting Studies • COCOCIN™ • Cococin™ is freeze-dried coconut water solids obtained from Cocosnucifera and is standardized to contain a minimum of 30% total carbohydrates and 2% total free amino acids. • Coconut water is the liquid endosperm of Cocosnucifera and is rich in proteins, amino acids, sugars, vitamins, minerals and growth hormones - essential to promote tissue growth. Nutrient rich Cococin™ promotes cell rejuvenation. • The role of coconut water solids in supporting cell growth. Cococin™ used to support the growth of human tissues such as hairfollicles. • Venocin® • Venocin® is obtained from the seeds of Aesculushippocastanum (Horse chestnut) and is standardized for 90% β-escin. Venocin® finds its use as a potential wound healing, anti-inflammatory, anti-edema and vasoprotective agent and is known to improve blood circulation. Venocin® helps relieve inflammation and thus strengthens and tones blood vessels to enable them to function properly. This in turn helps proper microcirculation of blood which is normally disturbed due to stress and aging.

36. Artonox™ • Artonox™ is obtained from dried heart wood of Artocarpuslakoocha. It is standardized for Oxyresveratrol 95% which is an analog of Resveratrol. Oxyresveratrol is found to be 32 fold stronger than Kojic Acid with regard to Skin lightening potential. Artonox™ has a broad spectrum antioxidant activity, showing a cumulative ORAC value of 19,735. • Boswellin® Super • Boswellin® Super is obtained from Boswelliaserrata gum and contains a minimum of 30% AKBBA (Acetyl 11-keto beta boswellic acid). AKBBA is reported to be the most potent anti-inflammatory ingredient among all the other boswellic acids. • AKBBA thus helps rejuvenate skin texture and tone along with the reduction of dark circles and puffiness under the eyes. • According to 2010 study published in Dermatologic therapy, fifteen women who applied a cream containing acid extracted from Boswellia should significant improvement in fine lines, wrinkle reduction, tactile roughness and other markers of aging skin . • Vitamin E Acetate • Vitamin E Acetate is a stable form of Vitamin E most often used in cosmetic formulations. Vitamin E protects cell membranes from damage by oxygen free radicals. It can prevent premature aging of the skin induced by UV irradiation and lipid peroxidation. • Studies have shown that topical use of tocopherol and alpha tocopheryl acetate are more effective than dietary supplementation in increasing the vitamin E content of the skin.

37. FAQ’s What is my skin type?Most women's skin type falls into one of six categories: dry; somewhat dry; normal; somewhat oily; oily; or combination. Skin type, which is determined by the amount of oil secretion, is hereditary. Environmental influences can tend to exacerbate conditions, but the different areas in the skin that produce oil and the amounts of oil produced are based on genetics. Why does stress affect my skin?Skin is the body's barrier to the outside world, both as a physical protector and as part of a complex immune defence system. stress interferes with the body's systems that repair and regulate the skin. For example, a loss in the skin's natural antioxidant defences due to stress can lead to accelerated ageing What causes skin ageing?Oxidation damage from sun and the environment is believed to be the number one cause of skin ageing. This damage affects collagen and elastin resulting in a loss of firmness and smoothness, the appearance of dark spots and discolourations, the formation of lines and wrinkles, and other ageing signs. I have oily skin. Do I still need a moisturizer? Yes, moisturizers play a vital role in a daily skin care regimen. If the skin is lacking moisture, simply speaking, little messages will get sent to the sebaceous glands (oil producing glands in the skin) alerting them to go into oil-producing overdrive. Essentially, by dehydrating the skin, more oil will be produced.

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