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Enhancing Research with VICTR Resources in 2013

Learn about Vanderbilt's CTSA program and VICTR development, explore new services like StarBRITE, Synthetic Derivative, Record Counter, and Subject Locator.

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Enhancing Research with VICTR Resources in 2013

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  1. Jumpstart your research in 2013: An Overview of VICTR Resources Tara Helmer, PA-C, MPH Research Services Consultant VICTR

  2. Provide brief background information on Vanderbilt’s Clinical & Translational Science Award (CTSA) and the development of the Vanderbilt Institute for Clinical & Translational Research (VICTR) Highlight some of the newer VICTR services and resources available through StarBRITE Objectives

  3. Vanderbilt received a CTSA in Sept. 2007; PI: Gordon Bernard; currently in Year 01 of our renewal Currently led by NCATS (Nat’l Center for Advancing Translational Science), the CTSA program supports a national consortium of medical research institutions designed to transform how biomedical research is conducted. Goals are to speed the transition of laboratory discoveries into treatment for patients, to engage communities in clinical research efforts and to train a new generation of clinical and translational researchers. 61 institutions across the country The Clinical and Translational Science Awards (CTSA) is a registered trademark of DHHS. 

  4. Implementation of our CTSA: Vanderbilt’s Institute for Clinical & Translational Research (VICTR) Goals of VICTR include: • Establish physical & virtual home for translational investigation • Stimulate communication, remove impediments and streamline administration • Develop a new generation of investigators trained in the bi-directional process of translational research • Foster collaboration and innovation by creating value-added review processes and pilot research

  5. StarBRITE: a main source of administrative streamlining • Widely used online research portal • > 4.5 million cumulative hits by about 15,000cumulative unique users to date

  6. Carousel StarBRITE Homepage

  7. What is the Synthetic Derivative? • Synthetic Derivative (SD) is the de-identified electronic medical record. SD 3.0 was launched with on February 25, 2013. SD 3.0 leverages the power of an IBM Netezza data warehouse appliance to provide faster, near-immediate counts as the user builds their search criteria. • Two components of the Synthetic Derivative: • Record Counter • Feasibility data • Aggregate counts • De-identified • No IRB required • Full Synthetic Derivative access • Access to the actual medical records • Requires IRB approval – Request for Non-Human Determination • Recommend you consult with SD team initially

  8. What is Record Counter? • Provides exploratory data figures and counts to members of the VU research community for research planning purposes and feasibility assessment.  • Allows the user to input basic medical data, such as ICD 9 codes or text keywords, e.g., lung cancer, as well as demographic information to determine the approximate number of records that meet those criteria.   • The results returned are not exact and are meant for a high level assessment of the available data. 

  9. RecordCounter: New Look – New Features What’s NEW? You will now be able to get counts for each specific criteria element as denoted to the right hand side of the search box (circled in red), summary counts for combined criteria (this OR that) indicated at the bottom of the group box (circled in blue), and a final Total count at the right corner of your search (circled in yellow).

  10. New & Improved SD – Data viz In the Summary tab and in the Vitals view, the new SD has new data visualization features that allow a reviewer to get a quick view of a subject’s longitudinal data.

  11. Annotations allow for easier identification and saving of covariate information during set review. Create your own set-based annotations that are sharable across the study team.

  12. What is Subject Locator?

  13. What is Subject Locator? • Starting with a set of people who have upcoming appointments in a user-determined set of clinics, Subject Locator identifies most-likely participants by screening StarPanel records for commonly used, discrete inclusion/exclusion criteria • Criteria include ICD9 and CPT codes, demographics, vitals, keywords, and medications • Subject Locator’s screening of potential study participants can reduce the number of patients reviewed manually from upcoming appointment lists and cross-referencing StarPanel. People with upcoming appointments • Examples from beta studies • Nephrology • Examined:   2598 • Candidates: 96 • (reduction - 96%) • Cleft Palate • Examined:   2490 • Candidates: 27 • (reduction - 99%) • Previous StudiesCardiology X 2 • (reduction - 95%) Inclusion / Exclusion Criteria SL

  14. How to move forward… • In order to use this tool:(See https://starbrite.vanderbilt.edu/recruitment/subjectlocator.htmlfor all you need to know about access) • Eligibility • Have a valid VUNet ID and password • Have an active IRB study and submit an IRB amendment (we can provide you with the language) • Must have access to StarPanel • How to Access: • 1) Complete the Access Request form on StarBrite • Forward your IRB approval letter • Let me walk you through it • Contacts: • Jon Scherdin (jon.scherdin@vanderbilt.edu) • Sarah Stallings (sarah.stallings@Vanderbilt.Edu) • Request early adopter status

  15. ROCKET is a web-based tool for sharing information and documents, allowing members of a workspace to collaborate more effectively and efficiently by building and sharing web pages.

  16. Pages (no limit) • Blue = private • Green = public • Add text, images, tables, checklists, headers, files (<128mb).

  17. Other resources available through StarBRITE Studios BioVU Pilot Funding Clinical Research Education Calendar Research Notifications Distribution List Tools for Grant Writing

  18. Upcoming Educational Sessions(Details on StarBRITE Education Calendar) • Recruitment Rodeo: March 11th, 1:30-3:30 • Clinical Immersion Boot Camp: March 22nd, 8:30-4:00 • New Processes for IDEs: March 27th, 3:00-4:00 • NIH Public Access Policy: April 12th, 12:00-1:00

  19. Questions/Comments? 3. 20 Research Support Services 343-7274 Research.Support.Services@vanderbilt.edu

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