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Cellular Transport Mechanisms: Plasma Membrane Functions

Explore the intricate processes of transport across plasma membranes, including passive and active modalities like diffusion, osmosis, and vesicular transport. Learn about the crucial role of pumps, receptors, and enzymes in cellular functions.

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Cellular Transport Mechanisms: Plasma Membrane Functions

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  1. Dr. mohammad khatatbeh Slides of lecture #4 Transport across plasma membrane

  2. Transport across Plasma Membranes

  3. Transport through plasma membranes Passive transport modalities -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion. -Facilitated diffusion: by carriers Differences in diffusion Kinetics between the previous modalities Equivalent Concentration of particles.

  4. Transport through plasma membranes Passive transport modalities -Osmosis: concept of osmotic pressure (Van’t Hoff’s law), Oncotic (Colloid-osmotic) pressure. Osmolarity, Osmolality Hydrostatic pressure and filtration

  5. Transport through plasma membranes Active transport modalities - Primary active transport (ATP-ase carriers or Pumps) (functions of pumps: Na+/K+ pump, Ca++ pump, H+ pump, H+/K+ pump). - Secondary active transport (Na+ dependent carriers) examples

  6. Transport through plasma membranes Active transport modalities - Vesicular transport: endocytosis, phagocytosis, transcytosis, pinocytosis and exocytosis and its control in secretory cells.-

  7. Active Transport Mechanisms • Primary active transport • Secondary active transport • Vesicular transport

  8. Types of Pumps • Na+/K+ pump • H+ pump • H+/K+ pump • Ca++ pump

  9. Phosphorylation & dephosphorylation

  10. Types of Pumps • Na+/K+ pump • H+ pump • H+/K+ pump • Ca++ pump

  11. The importance of pumps for cell functions

  12. Secondary Active Transport

  13. Secondary Active Transport • Co-transport • Counter transport

  14. Vesicular Transport

  15. Formation of vesicles at ER

  16. Endocytosis

  17. Phagocytosis

  18. Receptor mediated endocytosis

  19. Exocytosis

  20. Transcytosis

  21. Control of Transport and activity of Enzymes

  22. Receptors & Enzymes

  23. Receptors & Channels

  24. Receptors & G proteins

  25. Control of Exocytosis

  26. Summary of Lectures -Homeostasis -Control of body functions by feed-back mechanisms to keep homeostasis -Functions of Cell organells (ER, Golgi complex, Mitochondria, Lisosomes) -Cytoskeletal structures and Functions:

  27. Plasma membrane - Membrane structure and function of lipids of plasma membrane including phospholipids, cholesterol and PIP2) -Functions of Protein structures of plasma membranes (Channels, Carriers, Receptors, Pumps, enzymes, cell markers, G proteins, adhesion molecules) -Activation of chemical gated channels

  28. Transport through plasma membranes Passive transport modalities -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion. -Facilitated diffusion: by carriers Differences in diffusion Kinetics between the previous modalities Equivalent Concentration of particles.

  29. Transport through plasma membranes Passive transport modalities -Osmosis: concept of osmotic pressure (Van’t Hoff’s law), Oncotic (Colloid-osmotic) pressure.Osmolarity, osmolality Hydrostatic pressure

  30. Transport through plasma membranes Active transport modalities - Primary active transport (ATP-ase carriers or Pumps) (functions of pumps: Na+/K+ pump, Ca++ pump, H+ pump, H+/K+ pump). - Secondary active transport (Na+ dependent carriers) examples

  31. Transport through plasma membranes Active transport modalities - Vesicular transport: endocytosis, phagocytosis, transcytosis, pinocytosis and exocytosis and its control in secretory cells.-

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