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“Flow Characterization in a Microfluidic Compact Disc (CD) Platform for Clinical Diagnosis”. SURF-IT Fellow: Bryce Kubo Mentor: Professor Marc Madou Kameel Abi-Samra. What is microfluidics?.
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“Flow Characterization in a Microfluidic Compact Disc (CD) Platform forClinical Diagnosis” SURF-IT Fellow: Bryce Kubo Mentor: Professor Marc Madou Kameel Abi-Samra
What is microfluidics? http://www.ayhanozdemir.net/STEEL%20REINFORCED%20PE%20SPIRAL%20CORRUGATED%20PIPE%20MANUFACTURING%20LINE_files/image007.jpg Fig. 5 from M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.
What I am testing • Materials: Plastic vs. Silicon • Speed of Rotation: Slow vs. Fast • Width of the Channels: Wide vs. Narrow • Distance from Center: Close vs. Far
Burst Frequency ρωc2ṝ∆r = a(4γ/Dh) + b The angular frequency in which the liquid will break through the capillary valve and begin flowing M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.
How can a simple plastic CD be used for biomedical testing? • Mixing Liquids • Valving • Metering
Valving Fig. 2 from M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.
Metering Fig. 4 from M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.
SpinDEP Fig. 1 from R. Martinez-Duarte, et al, “The Integration of 3D Carbon Dielectrophoresis on a Rotating Platform”