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Microfluidic CD Platform for Clinical Diagnosis: Flow Characterization Study

Explore the use of a simple plastic CD for biomedical testing, focusing on materials, rotation speed, channel width, and flow dynamics. SpinDEP and metering valving are discussed, with practical applications demonstrated. Learn about the angular frequency and key burst frequency equation for efficient flow management.

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Microfluidic CD Platform for Clinical Diagnosis: Flow Characterization Study

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  1. “Flow Characterization in a Microfluidic Compact Disc (CD) Platform forClinical Diagnosis” SURF-IT Fellow: Bryce Kubo Mentor: Professor Marc Madou Kameel Abi-Samra

  2. What is microfluidics? http://www.ayhanozdemir.net/STEEL%20REINFORCED%20PE%20SPIRAL%20CORRUGATED%20PIPE%20MANUFACTURING%20LINE_files/image007.jpg Fig. 5 from M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.

  3. What I am testing • Materials: Plastic vs. Silicon • Speed of Rotation: Slow vs. Fast • Width of the Channels: Wide vs. Narrow • Distance from Center: Close vs. Far

  4. Burst Frequency ρωc2ṝ∆r = a(4γ/Dh) + b The angular frequency in which the liquid will break through the capillary valve and begin flowing M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.

  5. How can a simple plastic CD be used for biomedical testing? • Mixing Liquids • Valving • Metering

  6. Valving Fig. 2 from M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.

  7. Metering Fig. 4 from M. Madou, et al, “Lab on a CD,” Annual Rev of Biomed Eng, vol. 8, pp.601-628, 2006.

  8. SpinDEP Fig. 1 from R. Martinez-Duarte, et al, “The Integration of 3D Carbon Dielectrophoresis on a Rotating Platform”

  9. Any Questions?

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