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Heart Failure Update. "The new season will be all about scoring more goals than the opposition” Alvin Martin. "You can't do better than go away from home and get a draw." Kevin Keegan. NICE 2010. 1.1 Definition of chronic heart failure.
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"The new season will be all about scoring more goals than the opposition” Alvin Martin
"You can't do better than go away from home and get a draw."Kevin Keegan
NICE 2010 • 1.1 Definition of chronic heart failure Heart failure is a complex clinical syndrome of symptoms and signs that suggest impairment of the heart as a pump supporting physiological circulation. It is caused by structural or functional abnormalities of the heart. The demonstration of objective evidence of these cardiac abnormalities is necessary for the diagnosis of heart failure to be made
Right heart Failure – e.g. secondary to chronic lung disease High output heart failure Heart failure secondary to valvular heart disease Heart failure due to left ventricular disease
Chronic Heart Failure Jessup M, Brozena S. N Engl J Med 2003;348:2007-2018.
Angiotensinogen Sympathetic activation Renin Angiotensin I Angiotensin II Aldosterone Tachycardia vasoconstriction Spiro Salt retention
"Julian Dicks is everywhere. It's like they've got eleven Dicks on the field” Radio commentator
NICE Guidance Treatment of heart failure due to left ventricular systolic dysfunction
Angiotensinogen Sympathetic activation Renin Angiotensin I ACEI Angiotensin II Beta B’s ARB Aldosterone vasoconstriction Tachycardia Spiro Salt retention
"Gary always weighed up his options, especially when he had no choice” Kevin Keegan
NICE GuidanceTreatment of heart failure due to left ventricular systolic dysfunction
What disappointed me was that we didn't play with any passion. I'm not disappointed, you know, I'm just disappointed."Kevin Keegan
β-Blockers May Reduce Mortality and Risk of Exacerbations in Patients With Chronic Obstructive Pulmonary Disease Rutten F.H et al Arch Intern Med. 2010;170(10):880-887.
"He dribbles a lot and the opposition don't like it - you can see it all over their faces” Ron Atkinson
Heart Failure with Preserved Ejection Fraction (HFPEF) Heart failure due to diastolic dysfunction No agreed cut off point for preserved EF
"He reminds me of a completely different version of Robbie Earle."Mark Lawrenson
Echocardiographic diagnosis abnormal normal
Management of HFPEF • Control oedema • Rate control • Manage atrial fibrillation • Control Hypertension • Manage ischaemia
"In some ways, cramp is worse than having a broken leg."Kevin Keegan
Cardio renal syndrome • Reduced renal perfusion • Raised venous (intra-abdominal) pressure
Adverse effects of HF treatment Diuretic induced volume depletion Vasodilator induced hypotension
Effect of renal impairment on drug clearance Diuretic resistance ACEI / ARB Aldosterone antagonists Beta blockers
ACEI & ARBs reduce efferent vasoconstriction and hence reduce GFR Afferent arteriole Efferent arteriole Angiotensin
"Footballers are no different from human beings."Graham Taylor