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Peter Trabold, Ph. D., MBA Director, Business Development peter_t@zeptometrix.com 716.882.0920 Michael A. Hershfield Director, Sales & Marketing mhershfield@zeptometrix.com 508.553.5852.

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  1. Peter Trabold, Ph. D., MBADirector, Business Developmentpeter_t@zeptometrix.com716.882.0920Michael A. HershfieldDirector, Sales & Marketingmhershfield@zeptometrix.com508.553.5852

  2. NATtrol™ Molecular Controls (Nucleic Acid Test Control)Background:HIV, HCV, HBV Bloodscreening External Run ControlsTheory : Microorganisms require discrete Surface Protein Receptors to bind to and penetrate a host cell.Hypothesis:If we can modify those Surface Proteins such that the Microorganism can no longer bind to a host cell, then the Microorganism should be noninfectiousand…If we can modify those Surface Proteins without damaging the inner Nucleic Acids, then the modified Microorganism should still function in a Molecular based Assay.Conclusion: Two highly controlled Biomedical Procedures are used to modify the Surface Proteins and render the Microorganism noninfectious. Compounds that covalently modify proteins. Proteolytic Enzymes.

  3. NATtrol™ Molecular ControlsProduct Highlights:Non-Infectious Safe Purified Protein MatrixWhole Intact Organism Works across Platforms Mimics a true Clinical Specimen Not Synthetic RNAFull Process Controls for both Extraction & AmplificationRefrigerator Stable Simple storage and quick usage v. Frozen. From 2 to 8 °C unlike -20 °C Gel Pack v. Dry Ice1-2 year Stability Superior Shelf Life Longer Availability/ Reuse CapabilitiesFlexible Availability Available as Individual Analyte, Multiplexed or as a PanelCompatible Biotechnology Process is viable for Virus, Bacteria, Fungi, Parasite and BacteriophageBroad Patent Coverage Protected Technology

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