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------LpE------- * * --LpB--

A. ------LpE------- * * --LpB-- Tcas 4 exon 4 ADGNFEVTLATKATIY HQ GLVEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFK D 4 exon 4 ADGNFEVTLATKATIYSEGLVEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFK

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------LpE------- * * --LpB--

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  1. A ------LpE------- * * --LpB-- Tcas4 exon 4 ADGNFEVTLATKATIYHQGLVEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFK D4 exon 4 ADGNFEVTLATKATIYSEGLVEWKPPAIYKSSCEIDVEYFPFDEQTCVLKFGSWTYDGFK Tcas4 exon 4’ ADGNYEVTLMTKATVYYNGLVVWQPPAVYKSSCAIDVEFFPYDVQTCVLKLGSWTYDGFK D4 exon 4’ ADGHYEVTLMTKAIVYNNGLVIWQPPAVYKSSCSIDVEYFPYDVRTCILKLGSWTYDGFK LpD- -------TM2------- Tcas6 exon 3a DEKNQILTTNAWLNL Tcas6 exon 8a GVTILLSLTVFLNLVAEKIPTTSDAVPLI D6 exon 3a DEKNQILTTNAWLNL D6 exon 8a GVTILLSLTVFLNLVAESMPTTSDAVPLI Tcas6 exon 3b DEKNQLLITNIWLSL Tcas6 exon 8b GVTILLSLTVFLNLVAETLPQVSDAIPLL D6 exon 3b DEKNQLLITNLWLSL D6 exon 8b GVTILLSLTVFLNLVAETLPQVSDAIPLL Tcas6 exon 8c GVTILLSQTVFSLLVAHVITQTSDAVPLI D6 exon 8c GVTILLSQTVFSLLVGNVITKTSEAVPLL Tcas_RDL exon 3a GPPVEVGVTMYVLSISSVSEVLM Fly RDL exon 3a GPPVEVGVTMYVLSISSVSEVLM Tcas_RDL exon 3b GPPVEVGVTMYVLSISSLSEVKM Fly RDL exon 3b GPPVEVGVTMYVLSISSLSEVKM Tcas_RDL exon 3c GPPVVVGVTMYVLSISSLSEVQM LpF- --LpC--- Tcas_RDL exon 6a GYTMRDIRYKWNSGVKSVGISNEVELPQFRVLGHRQRATVINLTTG Fly RDL exon 6a GYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINLTTG Tcas_RDL exon 6b GYTMRDIRYKWNEGPNSVGVSNEVSLPQFKVLGHRQRAMEISLTTG Fly RDL exon 6b GYTMRDIRYKWNEGPNSVGVSSEVSLPQFKVLGHRQRAMEISLTTG Tcas_GluCl exon 3a DGPAIVRVNLFVRSIATISDIKM Fly GluCl exon 3a DGPAIVRINLFVRSIMTISDIKM Tcas_GluCl exon 3b DGPAIVRVNIFVRSISKIDDVTM Fly GluCl exon 3b DGPAVVRVNIFVRSISKIDDVTM Tcas_GluCl exon 3c DGPTVVNINFFLRSISKIDDYKM B C D

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