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- flubendiamide -

- flubendiamide -. The Next Generation in Lepidoptera Pest Management in Cotton Alan Hopkins, Shane Hand, Jon Mixson and Steve Krueger. Chemical Properties = The Nuts ‘n Bolts. 1 st compound of new chemical class (phthalic acid diamides)

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- flubendiamide -

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  1. - flubendiamide - The Next Generation in Lepidoptera Pest Management in Cotton Alan Hopkins, Shane Hand, Jon Mixson and Steve Krueger

  2. Chemical Properties = The Nuts ‘n Bolts • 1st compound of new chemical class (phthalic acid diamides) • Newly discovered mode of action = interrupts the Ca2+ balance as an ingested stomach poison • Considered harmless to pollinators and beneficials • Environmentally-friendly with favorable tox, ecotox, e-fate profile • IPM / IRM friendly • REI* = 12 hours (all crops) • PHI* = 1 day (all veggies) • Apps by air / ground / chemigation* • Highly rainfast (once dry) • Low rates = low env. loading • Excellent crop safety * Proposed labels

  3. Biological Characteristics Target Pests: Lepidoptera (broad-spectrum) – evaluating activity on secondary pests Other Target Crops: The active ingredient will also be registered for use in vegetables, grapes, fruits, tree nuts, citrus, and corn Mode of action: => unmatched larvicidal activity => orally-ingested intoxicant =>fast acting: rapid cessation of feeding (hrs) =>long lasting: rainfast and residual (weeks) =>novel biochemical target =>Ca2+ balance, stomach poison =>no known cross-resistance Formulation:BELT 4SC in cotton

  4. Insects Controlled • Highly active against larval stages of a broad range of lepidopteran pests. • Includes a host of difficult to control pests, including armyworm complex, looper complex, bollworm and budworm.

  5. Registration Timeline Data Completion: November, 2005 EPA Submission: April, 2006 Anticipated Reg: 2007 Full US Launch: 2008

  6. % Control of Fall Armyworm 70g (2oz) 88g (2.5oz) 105g (3oz) Tracer (2oz) 1 = Belt 4SC 70g (2oz) 2 = Belt 4SC 88g (2.5oz) 3 = Belt 4SC 105g (3oz) 4 = Tracer 2oz 7 DAA 14 DAA, 4 DAB Arlene Kurakowa,Bayer CropScience Fresno, California 21 DAA, 11 DAB 24 DAA, 14 DAB, 3 DAC 30 DAA, 20 DAB, 9 DAC

  7. Seasonal Mean for Evaluations 7DAA and Beyond % Control of Fall Armyworm 70g (2oz) 88g (2.5oz) 105g (3oz) Tracer (2oz) 1 = Belt 4SC 70g (2oz) 2 = Belt 4SC 88g (2.5oz) 3 = Belt 4SC 105g (3oz) 4 = Tracer 2oz Arlene Kurakowa,Bayer CropScience Fresno, California

  8. Evaluation 9 days after third application % Control of Bollworm and Tobacco Budworm(Evaluation of Damaged Squares) 70g (2oz) 88g (2.5oz) 105g (3oz) Tracer (2oz) 1 = Belt 4SC 70g (2oz) 2 = Belt 4SC 88g (2.5oz) 3 = Belt 4SC 105g (3oz) 4 = Tracer 2oz John Curtis,Bayer CropScience Molino, FL

  9. Influence on Seasonal Heliothine Larvae(Dr. Gus Lorenz, University of Arkansas) Applications on July 10 and 20. Data collected from 6 evaluations.

  10. Influence on Seasonal Heliothine Larvae(Dr. Gus Lorenz, University of Arkansas) Applications on July 10 and 20. Data collected from 6 evaluations.

  11. Influence on Seasonal Heliothine Damage(Dr. Gus Lorenz, University of Arkansas) Applications on July 10 and 20. Data collected from 6 evaluations.

  12. Influence on Seasonal Heliothine Damage(Dr. Gus Lorenz, University of Arkansas) Applications on July 10 and 20. Data collected from 6 evaluations.

  13. Summary • Flubendiamide is the first compound of the new chemical class: phthalic acid diamides. • Newly discovered mode of action: interrupts the Ca2+ balance as an ingested stomach poison. • Bayer CropScience expects registration of the active ingredient in several crops including cotton. • Provides excellent control of several lepidopteran pests of cotton, including the Heliothine complex. • Registration is expected in time for launch in 2008.

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