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Three different classes of ADP-ribose transfer reactions : NAD-dependent signaling pathways. NADH. NAD +. Protein - mono ADPR. Cyclic ADPR (cADPR). Protein - ADPR polymers. Signal transduction Cell-cell and cell-matrix interactions Chromatin silencing ( yeast ) Metabolism
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Three different classes of ADP-ribose transfer reactions :NAD-dependent signaling pathways NADH NAD+ Protein - mono ADPR Cyclic ADPR (cADPR) Protein - ADPR polymers Signal transduction Cell-cell and cell-matrixinteractions Chromatin silencing (yeast) Metabolism Ageing (yeast) DNA damage and stress signaling Calcium mobilisation Amé, J.-C., Jacobson, A. and Jacobson, M. (2000) in « Poly (ADP-ribosylation) reactions - from DNA damage and stress signaling to cell death ». De Murcia and Shall eds. Oxford University Press, pp 1- 34