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Lipemic sample

Lipemic sample. Dr.M.P.Saravanan,MD Associate professor KAPV Government Medical college,trichy,Tamil Nadu. Fasting Lipemic & Normal serum. Lipemic. Normal. Lipemic. Normal . Letters not visible. Letters can be read thro’ clear serum. Lipemic . Clear serum.

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Lipemic sample

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  1. Lipemic sample Dr.M.P.Saravanan,MD Associate professor KAPV Government Medical college,trichy,Tamil Nadu

  2. Fasting Lipemic & Normal serum Lipemic Normal

  3. Lipemic Normal Letters not visible Letters can be read thro’ clear serum

  4. Lipemic Clear serum Serum not transparent milky white appearance Letters visible through serum

  5. EDTA SAMPLE SHOWING MILKY WHITE PLASMA MILKY WHITE PLASMA

  6. 1/5 dilution of serum TGL & Chol values

  7. 1/20 DILUTION • TRYGLYCERIDE 10,500 MG/DL TOTAL CHOLESTEROL=1400 mg.dl Sodium – 128 mEq/dl (pseudo hyponateremia)

  8. Case history of this sample • 43yr/M came to hospital with c/o tiredeness,no h/o chest pain or any event of CAD in his family. Known diabetic • No alcohol intake in previous 3 days • Repeated the sample next day with fasting • Results remain the same

  9. Why is lipemic sample important? • Lipemic sample is a cloudy sample – scatters light in colorimetry- assay error with all chemistries • Matrix effect- less water component in serum or plasma due to more solid(lipid)- less electrolyte estimation- pseudo hyponateremia in direct ISEs

  10. Uncontrolled diabetes – where you get high values of TGL. • Congenital dyslipidemias- Go for Lipoprotein EPP • Look for cardiac risk- start dietary management & drugs if necessary

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