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Hormones produced by other Major organs. Kelly Diaz 3/4/14 A&P. Prostaglandins (PGs). This includes several groups indicated by the letters A-I (PGA-PGI) The chemical composition is derived form the fatty acid molecules
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Hormones produced by other Major organs Kelly Diaz 3/4/14 A&P
Prostaglandins (PGs) • This includes several groups indicated by the letters A-I (PGA-PGI) • The chemical composition is derived form the fatty acid molecules • Source: the plasma membranes of virtually all body cells stimulus is various (local, irritation, hormones, ect.) • This hormone has many targets, but only acts locally at site of release • Ex. - cause constriction of the respiratory passages ways - stimulate the muscles of the uterus and promote labor - promote inflammation and pain
Gastrin • The chemical composition is a peptide • Source: the stomach • To stimulate the hormone is food • The target is the stomach: inhibiting glands to release hydrochloric acid (HCI)
Intestinal Gastrin • Its is a peptide • The source is duodenum of the small intestine • The stimulus is food, especially fats • The target is the stomach and it inhibits HCI secretion and gastrointestinal tract mobility
Secretin • It’s a peptide • the source: duodenum • The stimulus is food • The target organs arethe pancreas which stimulates the bicarbonate-rich juice • The liver: increases release of bile • The stomach: reduce secretions
Cholecystokinin (CCK) • It’s a peptide • Source: duodenum • The stimulus is food • The organs it affects are the pancreas which stimulates the enzyme-rich juice • Gallbladder: stimulates expulsion of stored bile • Duodenal papilla: causes the sphincter to relax, allowing the bile and pancreatic juice to enter the duodenum
Erythropoietin • The chemical composition is glycoprotein • The source is the kidney • The stimulus is the hypoxia • The target is the bone marrow and they stimulate production of red blood cells
Active vitamin D3 • It’s a steroid • The source is the kidney(activates the provitamin D made by epidermal cells) • The stimulus is PTH • The target organ is the intestine stimulating active transport of dietary calcium across intestinal cell membranes
Atrialnatriuretic peptide (ANP) • It’s a peptide • The source is the heart • The stimulus is the stretching of atria of the heart • The target organs are kidney which inhibits sodium ion reabsorption and renin release • Adrenal cortex: inhibits secretion of aldosterone and that decreases blood pressure and volume
Leptin • It’s a peptide • Source: Adipose tissue • The stimulus is fatty foods • The target organ is the brain which suppresses appetite and increase energy expenditure
Resistin • It’s a peptide • The source adipose tissue • It doesn’t have a known stimulus • The targets are fat, muscle, liver: antagonizes insulin’s action on liver cells
Credits • Elaine N. Marieb- Essentials of Human Anatomy and Physiology