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The Red Hot Joint. James Bateman Rheumatologist. One Real Case from UHNS which tells you all you need to know about hot joints You are an FY1 in GP. 31 year old presents to his with a 1 day history of painful clavicle/sternum. Temporary patient at the surgery.
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The Red Hot Joint James Bateman Rheumatologist
One Real Case from UHNS which tells you all you need to know about hot jointsYou are an FY1 in GP • 31 year old presents to his with a 1 day history of painful clavicle/sternum. • Temporary patient at the surgery
What do you think? HPC PMHx Drug History Social History Systemic enquiry What are you going to do?
In A&E • What are you going to do?
What are you sending the fluid for? What will it tell you?
FY1 in GP • 70 year old lady, • Painful knee • AF on warfarin • DM type II • Hypertensive on BFZ and ACEi • Left knee is painful and swollen • Struggling to weight bear • What are you going to do?
In ED what are you going to do? History Investigations Treatments? Procedures? Imaging? In what order?
What Now? Do you need to do anything else?
Case 1 • 82 year old lady • Admitted acute on chronic knee pain 3-4 days • Recent excision of shin BCC with skin graft complicated by cellulitis • Ex Not unwell afebrile MEWS O • Warm, slightly tender knee effusion, tolerating 90 flexion • ? Wound infection started on antibiotics • CRP 187
Radiological abnormality? Differential diagnosis? Further investigations? Management? Case 1
Example • DB 45 year old man • PMH RA on sulphasalazine • 4 day history painful hot swollen red right big toe • Differential? • Investigations?
Case 3 • 82 year old man • PMH LVF,AF, TIA, BPH • DH Aspirin, bumetanide, ramipril, digoxin, statin • Referred with acute on chronic wrist pain needing MST • WBC 13, CRP 155, Cr 143, XR OA changes • Diagnosis and plan?
What single investigation is going to give you the answer? • Joint Aspiration: • Need: green needle • Need: Sterile field • Syringe • Microbiologist • White topped bottle
What are other differentials for monoarticular pain?
Monoarthritis - differential • Monoarticular sero-ve spondyloarthritis eg psoriatic and reactive arthritis • Monoarticular RA
Monoarthritis - differential • Haemarthroses (warfarin, bleeding disorders) • Trauma – fracture, internal derangement, haemarthroses
Others to think about • Osteonecrosis/AVN (steroids/alcohol/SLE) • Prosthetic joint - loosening, # or infection
Others to think about • Periarticular pathology • Cellulitis
Septic arthritis • 15-30 per 100,000 population • Fatal in 11% of cases in UK • Delayed or inadequate treatment leads to irreversible joint damage
Who gets septic arthritis? • pre-existing joint disease • prosthetic joints • low SE status, IV drug abuse, alcoholism • diabetes, steroids, immunosuppression • Skin lesions e.g. ulcers, particularly in context RA often source of infection
Which organisms? • common organisms Staphylococci or Streptococcus • Elderly & immunocompromised gram -ve organisms
Which organisms? • Anaerobes more common with penetrating trauma • Pseudomonas - IV drug abusers • young adults - significant incidence gonococcal arthritis
Who gets septic arthritis? • poor prognostic features: older pre-existing joint disease & presence of synthetic material within joint
What are the signs and symptoms of septic arthritis?
Symptoms & signs of septic arthritis • Symptoms usually present for < 2/52 • Typically hot, swollen, red tender joint with reduced range of movement, difficulty weight bearing • Night and rest pain • Large joints more commonly affected than small • majority of joint sepsis in hip or knee • Systemic upset (MEWS)
Symptoms & signs of septic arthritis • In pre-existing inflammatory joint disease symptoms in affected joint(s), out of proportion to disease activity in other joints. • 10% of cases > one joint • presence of fever not reliable indicator
Women>men Menses, pregnancy 1-3% arthritis 1day- weeks after sexual encounter Migratory (70%), Tenosynovitis (70%), monoarthritis (32%), polyarthritis (10%) Fever, Dermatitis (pustules, vesicular, haemorrhagic bullae, mac.papular) Gonococcal arthritis