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Fr. Gregor Mendel

Fr. Gregor Mendel. Father of Genetics 1822 - 1884. Pre-Mendelian Ideas on Inheritance. Blending Homunculus. Homunculus. Why was Mendel Successful?. Good Research Organism (pea plant) * Small, easy to grow in large numbers * short life cycle  could test several generations

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Fr. Gregor Mendel

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  1. Fr. Gregor Mendel Father of Genetics1822 - 1884

  2. Pre-Mendelian Ideas on Inheritance • Blending • Homunculus

  3. Homunculus

  4. Why was Mendel Successful? • Good Research Organism (pea plant) * Small, easy to grow in large numbers * short life cycle  could test several generations * Could cross or self-pollinate

  5. Could cross or self-pollinate(Why was this important????)

  6. Why was Mendel Successful? • Good Research Organism (pea plant) * Small, easy to grow in large numbers * short life cycle  could test several generations * Could cross or self-pollinate * Were “politically correct” (Explain!)

  7. Why was Mendel Successful? • Good Research Organism (pea plant) • Had good math/statistical background • Picked good pairs of traits to study:ex: Tall/shortex: (find for HW!)

  8. Mendel’s Experiments Experiment #1 • Created “pure breeding” tall plants • Created “pure breeding” short plants

  9. Experiment #1 (cont)Crossed “pure” tall x “pure” short

  10. Experiment #1 (cont)Crossed two F1 plants (Monohybrid Cross!)

  11. Now we know….

  12. Now we know….

  13. Same pattern • w “pure-breeding” purple & white:

  14. Same Pattern:

  15. Mendel’s Conclusions • Organisms inherit two “factors” for each trait, one from each parent • Principle/Law of Dominance • Principle/Law of Segregation • Law of Independent Assortment(Based on next cross…)

  16. Pure Purple Tall x Pure Short White P : F1 F2: (Homework):

  17. Test Cross:  Learn, then explain what it is & why Prof Dillon hates the following diagram:

  18. Text Rep of Test Cross:

  19. Extensions to Mendel • Incomplete dominance • Co-dominance • Pleiotrophy • Polygenetic inheritance

  20. Incomplete Dominance In snapdragons,R  red petals r  white petals

  21. Incomplete Dominance

  22. Incomplete Dominance

  23. Incomplete Dominance

  24. Incomplete Dominance If you mate a red with a white snapdragon… • RR X rr

  25. Incomplete Dominance If you mate a red with a white snapdragon… • RR X rr R r

  26. Incomplete Dominance If you mate a red with a white snapdragon… • RR X rr r R r R

  27. Co-dominance

  28. Co-dominance I A type A markers on surface of RBC I B  type B markers on surface of RBC i  neither A nor B markers on surface of rbc

  29. Co-dominance

  30. Co-dominance

  31. Co-dominance

  32. Co-dominance

  33. Co-dominance

  34. Co-dominance

  35. Co-dominance

  36. Polygenetic Each allele  melanin deposition The more genes, the more pigment (melanin).

  37. Remember:Environment influences Phenotype Same genotype!!

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