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Malawi HIV Quality Assurance Program 1990-1997 prepared by A. K. A. Barnaba

Malawi HIV Quality Assurance Program 1990-1997 prepared by A. K. A. Barnaba. Map and demographics of Malawi Project Objectives Program Description Types of samples Panel selection and lyophilization procedure. 6. Information management 7. Reporting of results 8. Sustainability

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Malawi HIV Quality Assurance Program 1990-1997 prepared by A. K. A. Barnaba

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  1. Malawi HIV Quality Assurance Program 1990-1997prepared by A. K. A. Barnaba

  2. Map and demographics of Malawi Project Objectives Program Description Types of samples Panel selection and lyophilization procedure 6. Information management 7. Reporting of results 8. Sustainability 9. Challenges faced 10.Future challenges. Structure of Presentation

  3. Map of Malawi TANZANIA ZAMBIA MOZAMBIQUE LILONGWE MOZAMBIQUE MALAWI BLANTYRE QUEEN ELIZABETH CENTRAL HOSPITAL

  4. Total Area: 118,484 Sq. Km. Demography Population: 9,800,000. Distribution Rural Population: 86% Urban Population: 14% City: Blantyre Population: 782,266 Pop. Growth Rate: 3% Economy : Agriculture. Life Expectancy: 39.3 years Adult HIV Prevalence: 16% estimated HOSPITALS Government: 27 Private: 28 HIV TESTING SITES. Total: 62 Government: 29 Private Hospitals: 28 Estate Clinic: 2 Military/Police: 2 Project Clinic: 1 Malawi Demographics Number of Sites

  5. Project Objectives • Set up National HIV reference laboratory. • Evaluate HIV test kits before they are introduced in the country. • Implement quality assurance program. • Expand quality assurance to other blood borne pathogens.

  6. Program Description • Collaboration between Queen Elizabeth Central Hospital,Lilongwe Central Hospital and Germany Technical Cooperation (GTZ). • Introduction of new testing techniques • Seven years duration

  7. Types of samples • Serum samples. • Lyophilized samples.

  8. 1. Identify 20 pints of blood . 2. Test the sera using available HIV test kits and Western blot. 3. Inactivate the serum specimens. 4. Select a panel of 20 samples Panel Selection and Lyophilization Procedure

  9. Panel Selection and Lyophilization Procedure continued…… 5. Test the panel with available kits in the hospitals. 6. Aliquot the sera into micro vials. 7. Keep samples in deep freezer ready for lyophilizing

  10. Panel Selection and Lyophilization Procedure continued…… 8. Assemble the lyophilizer and start lyophilizing

  11. Information Management • Filing • Data entry • Data analysis • Data for decision making

  12. Reporting of results • Medical Officer • Laboratory • Mail • Follow-up

  13. How is the program sustained? • Donor dependent • Dependence on one laboratory technician

  14. Past Challenges Staff • Ministry of Health & Population assigned a laboratory technician for 30% of his working time. Room • Laboratory and office space provided at Queen Elizabeth Central Hospital. Partial funds • Contribution to cost of quality control follow-up training.

  15. Future Challenges To ensure the high-quality, expansion and sustainability of national reference laboratory functions including quality assurance, it is necessary to: • Integrate the project into the national laboratory structure • Create dedicated positions for National HIV reference laboratory staff • Provide recruited staff with skills, budget and powers to improve testing quality nationwide

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