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Molecular and cellular biology. D. Gurarie. Biochemistry. Basic components: proteins, hydrocarbons, lipids, nucleic acids, other Basic processes: Metabolism : building (assembling, disassembling) intra/extra cellular components, removal of waste products.
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Molecular and cellular biology D. Gurarie
Biochemistry • Basic components: • proteins, hydrocarbons, lipids, nucleic acids, other • Basic processes: • Metabolism: building (assembling, disassembling) intra/extra cellular components, removal of waste products. • Energy transfer. Energy is typically stored in large molecules like ATP, or polymers (polysaccharides, lipids, proteins) • Catabolism: break-up of polymers into monomers (monosaccharides, fatty acids, amino acids), the excess energy being stored (ADP-> ATP) Anabolism synthesis of polymers from monomers (requires energy from ATP) • Signaling and cellular function/control (activation, proliferation, death) • Neural transmission • Many metabolic (and other biochemical) processes are controlled by ultra-efficient catalysts – enzymes (complex proteins)
Example: ADT-ATP kinetics Catabolism Anabolism ATP kinetics and structure