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TJJC. RESTORING THE JOY OF CHILDLESS COUPLES. Epidemiology. An increasing % of married couple suffer from childlessness due to infertility 10% of these childless couple are due to unexplained infertility A large % of these unexplained infertility can be traced to ovulation problems.
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TJJC RESTORING THE JOY OF CHILDLESS COUPLES
Epidemiology • An increasing % of married couple suffer from childlessness due to infertility • 10% of these childless couple are due to unexplained infertility • A large % of these unexplained infertility can be traced to ovulation problems
Possible Intervention includes; • Timed Intercourse -involves determination of ovulation -objective to have intercourse within 12hrs of ovulation
OVULATIONcan be adversely affected by • Abnormalities of the thyroid gland • Over production of prolactin(a hormone that leads to breast milk production) • Excessive male hormone (androgen) • STRESS-physical, psychological and extreme life style changes • Thereby making it extremely difficult todetermine ovulation
Present method of determination of OVULATION includes; • Basal Body Temp. Chart • Temp. Spike occurs after ovulation • Mid cycle pain - Sharp pain in the pelvic area usually lastingsome minutes or up to some hours • Cervical Mucus Changes • Should be Clear and Stretchy
Drawbacks of present techniques for determination of OVULATION • Cumbersome nature of the procedure • Inaccurate results • Process not easily observed in most women • Difficulty in interpretation of result • Messy procedure • Expensive
Creating a need for the birth of a novel product; • Simple and convenient to use • Guarantees accurate results • Hygienic procedure enhancing compliance • Can easily and accurately predict ovulation period in women • Very affordable
Mechanism of Action of • Detects Spike in Leutenizing Hormone in the urine in the middle of the Menstrual Cycle.
The Menstrual Cycle Start cycle Day 1-5. FSH (from brain) released into bloodstream - initiate follicles in ovary to grow. Day 6 - 11. One follicle grow faster than the others. Follicles start producing Oestrogen hormone. Follicles grow Oestrogen + FSH will prepare the womb (thicken) for later egg implantation. Day 12 - 14. Lutenising Hormone (LH) released for egg to “ripen” and burst from ovary. LH released 24 - 36 hours later, egg released from Ovary. LH & FSH drop drastically. Ovulation For 3 days, egg will travel in fallopian tube, waiting to be fertilized by a sperm. Continue….
The Menstrual Cycle……….continue Ovulation Unfertilized Egg expelled along with womb lining on the 28th day (menstruation) Fertilized Human Chorines Gonadotrophin (hCG) released for maintenance of the womb linings. Peak 60 - 80 days after conception. Few days to travel to womb. Get implanted Pregnancy Test + Positive !
The Ovulation Cycle 24-36 hours after LH surge Oestrogen FSH
WHEN TO… Start test ? Sample urine ?
-A Non Invasive Procedure • Collect urine once a day at about the same time every day. • For best result reduce liquid intake for 2 hours before collecting urine and do not urinate for about 4 hours
Easy to use • Remove the Test Strip from the sealed pouch • Immerse the strip into the urine with the arrow end pointing towards the urine. Do not immerse past the MAX (marker line)
TEST PROCEDURE Cont… • Take the strip out after 5 seconds and lay on a clean, dry, non-absorbent surface. • Wait for colored bands to appear. Depending on concentration of LH in the test specimen, positive may be observed in as little as 40 seconds. However, to confirm negative results, the complete reaction time of 10 minutes is required. • DO NOT READ RESULT AFTER MORE THAN 30 MINUTES!
Ease in interpretation of result • INVALID • NO LH SURGE i.e. Negative • LH SURGE i.e. POSITIVE
Positive RESULT means… • OVULATION WILL OCCUR IN THE NEXT 24-36 HRS!!! • So you know when to advice intercourse to achieve the desired goal! • Conception • Meeting for Couples Apart • AND…
MALE - X or Y CHROMOSONES FEMALE – X CHROMOSONES ONLY Aids determination of baby’s sex
RECALL THAT…. • X+Y Fusion = Male • X+X Fusion =Female • Y-sperm cells are light and swim faster across the cervix • X-sperm cells are heavy and swim slowly • Y-sperm cells die faster • X-sperm cells survive longer
SO.. • Intercourse some days before Ovulation- • More likely to yield X+X fusion i.e. Female • Intercourse immediately after Ovulation • higher probability of Y+X fusion i.e. Male
Summary of benefits • EASY AND CONVENIENT TO USE • NON INVASIVE AND HYGIENIC TECHNIQUE - ENHANCING COMPLIANCE • ACCURATE RESULT • SIMPLE TO INTERPRETE • VERY AFFORDABLE • AIDS NATURAL CONCEPTION • ALSO USEFUL IN NATURAL SEX SELECTION
With • You know with certainty when Ovulation will occur • You therefore also know when to advice intercourse • To Achieve conception and Sex Selection!
PRESCRIBE For Your Patients • You may just be God's hand waiting to touch some couples to restore JOY!
... a one–step test to determine the most fertile day to conceive! THANK YOU!