1 / 3

Predictor discovery in training set

MASS-Conductor. Prediction analysis (NSC, LDA, ROC). Cluster analysis. Predictor discovery in training set. Predictor confirmation in testing set. Pattern analysis in all set. 2. 3. 4. 1. Training set (5 CR, 5 PR of Enbrel ). Testing set (3 Anakinra CR). All set

forbes
Download Presentation

Predictor discovery in training set

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. MASS-Conductor Prediction analysis (NSC, LDA, ROC) Cluster analysis Predictor discovery in training set Predictor confirmation in testing set Pattern analysis in all set 2 3 4 1 Training set (5 CR, 5 PR of Enbrel) Testing set (3 Anakinra CR) All set (5 Enbrel CR, 5 Enbrel PR, 3 Anakinra CR) LCMS raw spectra Peak finding peak alignment feature extraction NSC Classifier training LDA Class prediction 2d hierarchical clustering heatmap plotting Predictors of 4 ~ 972 features Normalization FIVE-fold Cross-validation Predict Anakinra response Predictors of 972 or 32 features 106246 unique features Classify CR PR of Enbrel FIGURE 1

  2. FIGURE 2 A Feature number Classification error% Values of thresholds Enbrel PR CR 972 feature panel 32 feature panel B Anakinra CR

  3. Enbrel PR CR 972 feature panel 27 feature panel B Enbrel Anakinra Anakinra CR PR CR CR Predictive probability

More Related