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Infection in Oral & Maxillofacial Region. Pandect. Yu Chuang-Qi. Infection--- in oral & maxillofacial region. Pandect. Infection Conception Trait Anatomy Arising Route Mutation Influence factors Diagnosis Principles Treatment Principles. Infection---conception.
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Infection inOral & Maxillofacial Region Pandect Yu Chuang-Qi
Infection--- inoral & maxillofacial region Pandect • Infection Conception • Trait Anatomy • Arising Route • Mutation Influence factors • Diagnosis Principles • Treatment Principles
Infection---conception Infectious agent(bacteria) Host Inflammatory reaction protective and defensive Beneficial Elimination the infectious pathogen Repair tissue injury Harmful Hypersensitivity Autoimmune disease
Trait of anatomy • Oral and nasal cavity • Tooth • Space • Blood and Lymphoid system • Bacteria
Temperature + Moisture (Beneficial) Reproduction + Developing Trait of anatomy • Oral and nasal cavity • Maxillary sinus(上颌窦) Bacteria---Exist
Trait of anatomy Tooth Caries Pulpitis Apical infection Alveolar bone Soft tissue Fascial space
Trait of anatomy Fascial space(间隙)---loose connective tissue Among skin, maxillary and muscle • Purulent--- spreading way • Do not exist in healthy state • Become filling during infection
Trait of anatomy Blood and lymphoid system Beneficial Abundance Harmful Encephalic infection • Dangerous triangle • Lacking valves • Cavernous sinus Cavernous sinus thrombosis
Varied Numerous Streptococcus hemolyticus (溶血性链球菌) Staphylococcus aureus (金黄色葡萄球菌) Escherichia coli (大肠杆菌) Anaerobe (厌氧菌) Trait of pathogenic bacterium Flora(菌丛) • Sterile • Simple • Complex
Route of infection • Odontogenic infection • Adenogenous(腺源性) infection • Traumatic infection • Hematogenous(血源性) infection • Iatrogenic(医源性) infection
Odontogenic infection • Periapical infection • Pericoronitis(冠周炎)
Fistular(瘘) Septicemia(败血症) Acute-chronic Periapical infection Cellulitis (蜂窝织炎) Deep fascial space infection Intraoral soft tissue abscess (脓肿) Osteomyelitis (骨髓炎) Ascending facial-cerebral infection Periapical infection
Pericoronitis (冠周炎) Lower third molar
Infection---Arising • Host--- defense system • Microbe---virulence quantity • Local circumstance Balance Imbalance Scale
Mutation • Influence factors • Changing directions
Influence factors • Host--- defense system • Microbe---virulence quantity • Treatment strategy
Changing directions • Localization and recovery • Acute chronic • Diffusion Blood system---Septicemia lymphoid system---Lymphadenopathy From submandible space infection to chest region
How to diagnose? • Local Signs and Symptoms • Systemical Signs and Symptoms Signs and Symptoms
Local Signs and Symptoms • Pain • Swelling • Surface erythema • Pus formation • Limitation of motion Locally
Systemical Signs and Symptoms • Fever • Lymphadenopathy • Malaise • Toxic appearance • Elevated white blood cell count
How to treat? • Acute stage • Chronic stage
Acute stage • Host • Antibiotic therapy • Surgical drainage and incision
Migration of white blood cell Production of antibodies Most important factor --- final outcome The infections--- cured by the host, not by antibiotics Host Defense Mechanisms Critical Principles
Principles for choosing appropriate antibiotic • causative organism(致病菌) • sensitivity • specific, narrow-spectrum antibiotic • least toxic antibiotic • drug history(success, allergic and toxic) Antibiotic era
Principles of antibiotic administration • Proper dose • Proper time interval • Proper route of administration(oral, parenteral) • Combination antibiotic therapy
Surgical drainage and incision • How to judge the pus formation? • Purposes of surgical drainage and incision • Principles of surgical drainage and incision
Three stages Inoculation Cellulitis Abscess Duration--- >5 days Palpation---Fluctuant Appearance---Reddened Needle aspiration B-ultrasound CT How to judge the pus formation? Characteristic
Purposes of surgical drainage & incision • Rid the body of toxic purulent material • Decompress the tissues • Allowing better perfusion of blood containing antibiotics and defensive elements • Increased oxygenation of the infected area
Infection in multi-space Ludwig’s angina
Principles of surgical drainage & incision • Place the incision in an esthetically acceptable • Place the incision in a dependent position to encourage drainage by gravity • Dissect bluntly through deeper tissues and explore all portions of the abscess • Place a drain and stabilize it with sutures
Chronic stage Surgical removal of the focus(病灶) • Lesion tooth---Impacted tooth • Osteomyelitis
Conclusion Infection in oral & maxillo-facial region • The trait of Infection • Odontogenic infection • mutation of infectious • Diagnosis of the infection • Diagnosis of the abscess formation • The principles of the treatment