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Ancylostoma duodenale. Taxonomy. Kingdom : Animalia Phylum : Nematoda Class : Rhabditea Order : Strongylida Family : Ancylostomatidae Genus : Ancylostoma Species : duodenale . Old world hook worm Causative agent of ancylostomiasis
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Taxonomy • Kingdom : Animalia • Phylum : Nematoda • Class : Rhabditea • Order : Strongylida • Family : Ancylostomatidae • Genus : Ancylostoma • Species : duodenale .
Old world hook worm • Causative agent ofancylostomiasis • Parasitic description by Dubini • Mode of infection by Loose • Habitat : lumen of small intestine
Morphology : • Adult worm : cylindrical , greyish white , slightly curved . • ant. end : bent slightly in same direction of body curve . • Buccal capsule : 6 teeth . • Post. end : bell shaped – copulatory bursa – holding the female worm . • Copulatory bursa : 13 rays in 3 lobes .
Buccal capsule Copulatory bursa Adult worms
Difference b/w male and female Male Female
Egg : • Size : 60 mc in L ,40 mc in B . • Shape : oval • Non bile stained • Thin shelled • 8 blastomeres , clear space .
Filariform larva • Non feeding form • Slender • 500 – 600 mc in L • Pointed tail • Shorter oesophagus • Infective form .
Pathogenesis • Source : human faeces • Host : man • No intermediate host • Route : Penetration Ingestion Transmammary Transplacental .
Clinical manifestations • 20 – 40% Asymptomatic Skin manifestations : ground itch small itchy papules Site : around feet , b/w toes . Symptoms : intense itching edema erythema rash .
Respiratory manifestations : • Low grade fever • Mild cough , pharyngitis • dyspnea , pneumonia . Intestinal manifestations : • low grade fever , anaemia , git disturbances • Anaemia : hypochromic microcytic types – mild , moderate , severe .
Lab diagnosis • specimen : stool • Methods : microscopy – direct wet mount concentration – formalin ether salt flotation kato katz method culture – harada mori method . • imaging methods : x – rays .
Treatmant • Mebendazole • Pyrantel pamoate • Thiabendazole .