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CPC CASE. Dr. Sara K. Ornazian D.O. Core Faculty McLaren Oakland Pontiac, MI. Welcome to Vegas!. What do we know. 73 year old female Altered, abdominal pain, sepsis alert VSS
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CPC CASE Dr. Sara K. Ornazian D.O. Core Faculty McLaren Oakland Pontiac, MI
What do we know • 73 year old female • Altered, abdominal pain, sepsis alert • VSS • Discomfort, dry mucus membranes, coarse breath sounds, increased bowel sounds with guarding and rebound, heme positive and disoriented
Differential Diagnosis • Sepsis • Encephalopathy • GI Bleed • Liver Failure Stroke Thyroid disease Toxicological syndrome
Empty our satchel.. • WBC 15.7 • INR 2.2, PT 24.7, PTT 31 • K+ 2.5 • AG 7 • AST/ALT normal • Troponin negative • UA- blood, ketones, protein • EKG- sinus tachycardia • Medications
New differential • Sepsis- where is the source?? • Encephalopathy • GI Bleed • Chronic Salicylate Toxicity • Stroke • DIC
Images • Chest X-ray – Intubated, No acute process • CT Head – No acute process • CT Abdomen/pelvis – diverticulosis, thinning of the renal cortex - ATN
Top 3 differential • 1.) Sepsis • 2.) GI Bleed • 3.) Chronic Salicylate Toxicity
What I wish I had.. • A more detailed neurological exam • TSH and Free T4 • Salicylate level, Acetaminophen level, ABG • MRI
Final Diagnosis • Chronic Salicylate Toxicity
References • Leatherman J, Schmitz P. Fever, Hyperdynamic Shock, and Multiple System Organ Failure. A Pseudo- Sepsis Syndrome Associated with Chronic Salicylate Intoxication. Chest. 1991 Nov; 100(5) 1391-1396. • Yip L, Compiler. Tintinalli’sEmergency Medicine: selected bibliography. New York (NY) McGraw Hill; c2011. Chapter 183, Aspirin and Salicylates. 1243-1246.