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Simulating A Gene Regulatory Network (GRN)

Simulating A Gene Regulatory Network (GRN). A Delay Flip-Flop Implementation. Outline. Simulation Hill Equation Michaelis-Menten BioD Results. Outline. Simulation Hill Equation Michaelis-Menten BioD Results. Simulation. Why do we simulate ?. Simulation. Cost effective Fast

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Simulating A Gene Regulatory Network (GRN)

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  1. Simulating A Gene Regulatory Network (GRN) A Delay Flip-Flop Implementation

  2. Outline • Simulation • Hill Equation • Michaelis-Menten • BioD • Results

  3. Outline • Simulation • Hill Equation • Michaelis-Menten • BioD • Results

  4. Simulation • Why do we simulate ?

  5. Simulation • Cost effective • Fast • Proven method • An “analytic” model is appropriate when mathematics can be used to find the exact (deterministic) or probable (stochastic) values of the measures of performance. • We cannot test

  6. Outline • Simulation • Hill Equation • Michaelis-Menten • BioD • Results

  7. Outline • Simulation • Hill Equation • Michaelis-Menten • BioD • Results

  8. Hill Equation

  9. Hill Equation

  10. Hill Equation

  11. Hill Equation

  12. Hill Equation

  13. Outline • Simulation • Hill Equation • Michaelis-Menten • BioD • Results

  14. Outline • Simulation • Hill Equation • Michaelis-Menten • BioD • Results

  15. Michaelis-Menten http://en.wikipedia.org/wiki/Enzyme_kinetics

  16. Outline • Simulation • Hill Equation • Michaelis-Menten • BioD • Results

  17. Outline • Simulation • Hill Equation • Michaelis-Menten • BioD • Results

  18. BioD

  19. BioD

  20. BioD

  21. BioD

  22. BioD

  23. BioD

  24. BioD

  25. BioD

  26. BioD

  27. BioD

  28. BioD

  29. BioD

  30. BioD

  31. BioD

  32. Law of Mass Action

  33. BioD

  34. BioD

  35. BioD

  36. BioD

  37. BioD

  38. BioD

  39. BioD

  40. Outline • Simulation • Hill Equation • Michaelis-Menten • BioD • Results

  41. Outline • Simulation • Hill Equation • Michaelis-Menten • BioD • Results

  42. Results

  43. BioD

  44. Results

  45. Results

  46. Results

  47. Results

  48. Results

  49. BioD

  50. Results

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