Medical imaging with a photogate: an activity for high school and college students

1. Medical imaging with a photogate: an activity for high school and college students Elliot Mylott, Ryan Klepetka, Justin C. Dunlap and Ralf Widenhorn Physics Department, Portland State University, Portland, OR Operation Artifacts and Windowing Abstract • When the photogate becomes blocked, the program… • calculates the equation of the line between the source and detector of the photogate • enters the projection data along that original line • The inputs of the program are • the distance between the rotational axis and the origin, also called the focus-center distance (FCD) • the angle between the FCD line and the negative x-axis q • the angle between the FCD line and the scanning line f • Image artifacts: • Caused by either the reconstruction algorithm or the scanning technique • Can be incorporated into the laboratory session as they are important considerations in medical scanners as well • The most common artifacts are… • Unwanted data that does not correlate to either the cylinders or the enclosure • “Blurring” (amplitude on reconstruction proportional to 1/r) • “Afterglow” (misplaced data caused by short scan times) We present a laboratory activity in computed tomography (CT) primarily composed of a photogate and a rotary motion sensor that can be assembled quickly and partially automates data collection and analysis. We use an enclosure made with a light filter that is largely opaque in the visible spectrum but mostly transparent to the near IR light of the photogate (880nm) to scan objects hidden from the human eye. This experiment effectively conveys how an image is formed during a CT scan and highlights the important physical and imaging concepts behind CT such as electromagnetic radiation, the interaction of light and matter, image artifacts and windowing. CT and Back Projection Reconstruction Program • Windowing • Emphasizes differences in attenuation characteristics • Done by adjusting the relative values of the gray scale • Figure 8 shows the same data as figure 6 after applying a window. Note that the lower boundary of the grey scale is higher than that in figure 6, which obscures the unwanted data. Figure 3. CT geometry • X-rays from the source are attenuated by objects in the scanned area, which is recorded as projection data • That data is spread back onto a reconstruction of the scanned area • This process is completed multiple times as the source/detector assembly rotates about the scanned area • After multiple back projections an image of the original object(s) forms. Complete Scan Figure 8. The same data from figure 6 after applying a window. Figure 5. Positions of three cylinders in the enclosure (0.6 cm in diameter) References Figure 1. Basic reconstruction technique of CT [1] Buzug T M 2008 Computed Tomography: From Photon Statistics to Modern Cone-Beam CT (Berlin: Springer) pp 2, 201, 207, 485, 85,437 [2] Delaney C and Rodriguez J 2002 A simple medical physics experiment based on a laser pointer Am.J. Phys. 70 1068-70 [3] Murphy, S 2010 Basic Apparatus for CT Analogy, 2010 March 5, http://web.phys.ksu.edu/mmmm/instructor/. [4] Wolbarst, AB 2005 Physics of Radiology (Madison, WI: Medical Physics Publishing) p 409 [5] Kane SA 2003 Introduction to Physics in Modern Medicine (Abingdon, UK: Taylor & Francis) pp 189-195 Apparatus • Principal components were Vernier photogate and rotary motion sensor • Instead of X-rays, we used a near IR light source to simulate a CT scanner • The enclosure is a Congo Blue light filter, which is largely opaque in the visible spectrum but mostly transparent to the near IR photogate light. Figure 4. LabVIEW user interfaces (manual and simulated) Figure 6. Final image of cylinders in figure 4 (36 scans, 20 min scan time) Figure 7. Scans of the cylinders as shown in figure 5 taken in 10o increments over q =150o Conclusion • The LabVIEW program… • Collects and displays data in real time • Forms image step by step (figure 7). • Comes with a simulated CT scanner that uses the same algorithm • Quick scans of multiple combinations of object sizes and positions. • Explores the effects of the three parameters (FCD, f and q) on the final image • An effective graphical demonstration of how back projection forms an image. • The images in figure 6 and 7 are of three identical cylinders, each with a diameter of 0.6 cm, placed in the enclosure as shown in figure 5. The large ring around the cylinders in the images is the opaque enclosure which reflects the light from the photogate at shallow angles effectively “blocking” it. • The time needed to complete a full scan is dependent on… • The number of passes (each having a unique q) • The rotational speed of the photogate • The resolution of the reconstruction. We have constructed a simple, safe apparatus that effectively demonstrates the basic mechanism and concepts behind CT scans. It is comprised of a photogate, rotary motion sensor, and other equipment commonly found in most physics teaching labs. The setup can be completed in minutes and scan times are short enough that multiple objects can be imaged in a single session. The activity is appropriate for high school and college level physics or biology courses. This activity gives students a chance to learn about trigonometry, electromagnetic radiation, radiographic imaging, image analysis and windowing. Figure 2. CT apparatus and light filter