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Opioid Free Anesthesia. Tom Baribeault MSN CRNA. What is Opioid Free Anesthesia. New technique of anesthesia administration Opioid-free intra-operatively Maintain hemodynamics with medications that protect the nervous system Acute surgical pain management Treat the cause of the pain. Why.
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Opioid Free Anesthesia Tom Baribeault MSN CRNA
What is Opioid Free Anesthesia New technique of anesthesia administration Opioid-free intra-operatively Maintain hemodynamics with medications that protect the nervous system Acute surgical pain management Treat the cause of the pain
Why Safer anesthetic Less respiratory depression Acute surgical pain control Prevent chronic pain Avoid side effects of opioids Patient satisfaction Shorter hospital stay $$$ Reduce opioid addiction/dependence
Preconceptions Opioids are: Necessary: hemodynamic control and pain management Beneficial: improve the patient experience Safe: respiratory depression and other side effects can be safely managed Adequate: pain is well controlled
Special Populations Respiratory Complex Pain Management Opioid users/abusers Recovery High risk chronic pain PONV Cancer Elderly
Anatomy Peripheral Nerves A Beta A Delta C Spinal Nerves Rexed Lamina I Rexed Lamina V
Anatomy Rexed Lamina I Midbrain Periaqueductal Grey Rostral Ventromedial Medulla Descending Fibers Rexed Lamina V Thalamus Pain Matrix
Natural Inhibition Periaqueductal Grey Rostral Ventromedial Medulla A Beta Inhibition
Hyperalgesia Primary (Peripheral) Sensitization Inflammation Induced Central Sensitization Secondary (Central) Sensitization Allodynia Opioid Induced Hyperalgesia
Hyperalgesia Primary (Peripheral) Sensitization Inflammation Induced Central Sensitization Secondary (Central) Sensitization Allodynia Opioid Induced Hyperalgesia
History Balanced Anesthesia Fentanyl Multimodal Therapy Pre-emptive Analgesia Preventative Analgesia
Peripheral and Central Inflammation Steroids Nsaids/Coxibs Cannabinoids? Local Anesthetics
Central Sensitization Glutamate Ketamine N2O Magnesium Gabapentinoids Substance P Clonidine Dexmedetomidine Tizanidine
Central Sensitization Anti-depressants Duloxetine Trazodone Tramadol Cyclobenzaprine Amitriptyline
Analgesics Local Anesthetics Regional/Neuraxial Lidocaine infusion Acetaminophen Beta Blocker Opioids
Plan Intra-operative Local Anesthetics A2 agonist NMDA antagonist Beta Blockers
Plan Post-operative Acetaminophen NSAID/Cox 2 Gabapentinoid Anti-depressant Opioid Infusions Lidocaine A2 Ketamine
OFA Expectations Normotensive Increased respiratory rate Initial wake up slower Less pain/more responsive to opioids
Resources Goopioidfree.com info@goopioidfree.com