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Benign breast diseases. Dr Maryam Tabatabaeian. Benign breast lesions. Non proliferative no risk for malignancy cysts,fcc without hyperplasia,epithalial calcifications,apocrine papillary changes, Proliferative without atypia 1/5-2 × risk
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Benign breast diseases Dr Maryam Tabatabaeian
Benign breast lesions • Non proliferative no risk for malignancy cysts,fcc without hyperplasia,epithalialcalcifications,apocrine papillary changes, • Proliferative without atypia 1/5-2× risk Ductalhyperplasia,papilloma,sclerosingadenosis,radialscar,fibroadenoma • Proliferative with atypia 3/7-5/3× risk ADH,ALH
Fibroadenoma B3 Single or multiple(FH) Most masses in women<30yrs Size>3cm,age>35yrs,FH+,growth rate>30% in 3 months biposyor excision if patients is stressed Giant fibradenoma>5cm benign 17%regression without therapy Macrolobulation is normal microlobulation needs biopsy Complex fibradenoma surgery
Cysts • Simple cyst B2 thin wall,single or multiple,clearcontent,size<3cm no risk ,routine follow up • Complicated cyst B3 thick wall<5mm,septation,internal echo,no flow in dopplersono 0/4% malignancy hematoma,absess,fatnecrosis,galactocele • Complex cyst B4 Thick wall>5mm,size>5cm,mass component,shadow absses,apocrinemetaplasia,oilcyst,fatnecrosis,malignancy 20-40% malignant
Mass • <30 yrs mostly benign 75%fibroadenoma • >50 yrs half malignant • <30yrs sonogram • >35 yrs mammogram • BIRADS 3 without riskfactorfollow up • BIRADS 4 or B3 with risk factor biopsy • Biopsy CNB
Mass • Mammogram 20% false negative 40- 50 yrs 10% false negative>50 yrs After a negative biopsy follow up each 6 months to 2 yrs is mandatory
Thickening 2 dimentional lesion Mammogramm and sonogram and other complementary test as indicated 10-17% need biopsy 50% of biopsies are malignant no need to medical treatment
Papilloma is benign but needs surgery because of nipple bleeding Papillomatosis : .5 papilloma in one segment no risk for malignancy
ADH,ALH • Gail model for risk assesment • No OC or HRT • Flat epithelial hyperplasia exscision, less risk for malignansy
hamartoma • Fibroadenolipoma malignant tranformationsugery
Adenoma Pure epithelial component,tubular and lactating subtype No risk for malignancy Surgery in suspicious forms
Granulomatous mastitis non TB granulomatosis Presents as mastitis or inflamation and mass Dx CNB Treatment :treatment of absses and then corticosteroids in refractore cases Surgery has malconvinient results and deformities cause to unnecessary mastectomies