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Maximum home b lood pressure: a novel indicator of target-organ damage in hypertension

Maximum home b lood pressure: a novel indicator of target-organ damage in hypertension. B lood pressure variability has recently been shown to be a strong predictor of stroke and cardiovascular events, independently of the mean systolic blood pressure level. 1

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Maximum home b lood pressure: a novel indicator of target-organ damage in hypertension

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  1. Maximum home blood pressure: a novel indicator of target-organ damage in hypertension Blood pressure variability has recently been shown to be a strong predictor of stroke and cardiovascular events, independently of the mean systolic blood pressure level.1 The clinical implication of variability in blood pressure, as measured by home blood pressure monitoring, has never been reported. A new study has investigated the association between maximum home blood pressure and target-organ damage in 356 never-treated hypertensive subjects. 1. Rothwell PM et al. Lancet. 2010;375:938-948. 2. Matsui Y et al. Hypertens, 2011;57: in press

  2. Maximum home systolic blood pressure measurements were observed up to 50 times per day Number of episodes per/day Matsui Y et al. Hypertens. 2011;57: in press

  3. High incidence of maximum home systolicblood pressure isassociatedwith a highdegree of cardiac and vascularremodeling Matsui Y et al. Hypertens. 2011;57: in press

  4. Conclusion This study provides additional information on the importance of blood pressure stabilization to prevent cardiovascular complication in hypertensive patients: • Transiently high blood pressure readings at home should be taken seriously as meaningful indicators for hypertensive damage in the heart and artery.1 • The variability in systolic blood pressure can be simply assessed by home blood pressure measurements.1 • This study confirms, that effective antihypertensive treatment should not only reduce, but also stabilize blood pressure.2 1. Matsui Y et al. Hypertens. 2011;57: in press; 2.Rothwell PM. et al. Lancet. 2010;375:938-948.

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