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CASE PRESENTATION. By: Dr. SHAMSHAD KHAN TMO Radiology HMC. Case. A 23 year old female came with pain in right hypochondrium. LFT ’ s were normal Ultrasound abdomen was done Which is as …….
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CASE PRESENTATION By: Dr. SHAMSHAD KHAN TMO Radiology HMC
Case • A 23 year old female came with pain in right hypochondrium. • LFT’s were normal • Ultrasound abdomen was done • Which is as …….
Polycystic liver disease • About 10 to 13 % of individuals have cysts in liver either single or multiple • Mostly are asymptomatic • LFT’s are normal in most cases • Approx 45 % occur with polycystic kidney disease
LIVER LESIONS on ULTRASOUND • Two main types . Benign lesions . Malignant lesions
BENIGN • Cystic which may be • Simple Cysts • Abscesses • Parasitic cysts
Cont…… • Hepato-Billiary Cystic lesions • Hemangioma • Caroli’s disease • Peliosis • Choledochal cyst • Veno -occlusive disease
Cont……… • Hepatocellular • Focal Nodular Hyperplasia • Adenoma
MALIGNANT • Hepatocellular carcinoma • Fibrolamellar HCC • Metastasis • Lymphoma • Hepatoblastoma
CYSTS • Most common lesions • Have three main characteristics Anechoeic lumen Increased through transmission Well enhanced posterior wall cont….
May be multiple as in poly cystic liver
Cysts may be complex if they have Internal echoes Thick wall Septations Calcification cont………
Complex cysts include Hematomas Abscesses Echinococcus Hemorrhagic tumors
Abscesses • May be Bacterial , Fungal or amoebic Bacterial abscesses are caused due to intestinal infection like appendicitis and diverticulitis or even caused by endocarditis.
Cont… • They appear as complex fluid collections with mixed echogenisity. • They may mimic solid hepatic masses but the presence of through transmission will provide clue to liquefied nature of the mass. • They may calcify with healing
Amoebic liver abscess • Usually single but can be multiple • Typically located in right lobe of liver • 30 to 70% are single • Appear as homogenous hypoechoeic lesions, round or oval with well defined borders
Amoebic liver abscess • Initial stage
Amoebic liver abscess • Recently formed cyst
Amoebic abscess of duration
Fungal Abscesses usually occur in immunocompromised patients Most common organism is candida Mostly cause very small lesions (microabscesses) Larger lesions may occur
cont…… • Typical appearance is target lesion with central echogenic region and peripheral hypoechoeic halo. • Every lesion may have hypoechoeic focus centrally caused by necrosis and fungal elements.
Ultrasound features of hepatic candidiasis • “Wheel within a wheel” peripheral hypoechoeic area inner echogenic wheel central hypoechoeic nidus • Bull’s eye Hyperechoeic centre Hypoechoeic rim • Uniformly hypoechoeic progressive fibrosis • Echogenic calcification representing scar formation
Multiple hypoechoeic lesions in acute mylogenous leukemia
Hepato-Billiary Vascular Cysts • Hepato-Billiary Vasculature can also appear as Cysts as seen in Aneurysms Arterio-portal and Veno-portal fistulas Caroli’s disease Choledochal cyst
Caroli’s disease • Rare inherited disorder characterized by dilatation of the intrahepatic bile ducts • Two types of Caroli disease simple or isolated case where bile ducts are widened by ectasia 2nd is complex called Caroli syndrome associated with hypertension and congenital hepatic syndrome
Caroli’s disease with multiple intra hepatic cysts
Caroli disease in 9 year old girl
Choledochal cyst • Congenital disease causing cystic dilatation of bile ducts • Appears in 1st year of life with jaundice and sometimes with palpable mass
Choledochal cyst in 1 year old boy
Parasitic cysts • Usually caused by Ecchinococcus granulosus • Liver is most commonly affected organ Have an external membrane ectocyst and an internal germinal layer called endocyst.
cont…… • In addition forms a cyst around called pericyst. • Appear on ultrasound as a simple cyst with internal daughter cysts with detatched membranes , with internal debris and cysts, and with internal or peripheral calcification.
Hydatid Cyst with Detached membranes
BENIGN HEPATOCELLULAR LESIONS • Hemangiomas • Most common benign liver neoplasm occuring in 7 % of adults • More common in women than in men • Usually single but 10 percent are multiple
cont……… • If small, they are asymptomatic • But if large, they have symptoms due to mass effect.
Small hemangiomas ( less than 3cm ) typically appear as homogenous hyper echoeic mass with sharp and smooth margins. • If large, they may be atypical as a result of thrombosis, fibrosis and necrosis. Calcification can occur but is rare
cont…… • Some percentage of atypical hemangiomas may have hyperechoeic periphery and hypoechoeic centre.This is REVERSE TARGET SIGN characteristic of hemangiomas and is rarely seen in malignant disease.
Reverse Target sign.