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Supplementary Figure 1. A. B. C. Supplementary Figure 2. Supplementary Figure 3. A. PHTX-14B Day 10. B. MDA-MB-231 Day 10. Supplementary Figure 4. Vehicle. MLN8237 20mg/kg QDx3/wk. Treatment Period. 2500. 2000. 1500. Average Tumor Volume (mm^3). 1000. 500. 0. 0. 10. 20.
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Supplementary Figure 1 A B C
Supplementary Figure 3 A PHTX-14B Day 10 B MDA-MB-231 Day 10
Supplementary Figure 4 Vehicle MLN8237 20mg/kg QDx3/wk Treatment Period 2500 2000 1500 Average Tumor Volume (mm^3) 1000 500 0 0 10 20 30 Days Paclitaxel 20mg/kg MLN8237 20mg/kg QDx3/wk Paclitaxel 20mg/kg