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Connective Tissue Disorders

Connective Tissue Disorders. Naomi Reay University of Leeds 2002. Aims. Awareness of the types of connective tissue diseases Insight into the problems encountered by these patients and appropriate management strategies Appreciation of Systemic Sclerosis.

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Connective Tissue Disorders

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  1. Connective Tissue Disorders Naomi Reay University of Leeds 2002

  2. Aims • Awareness of the types of connective tissue diseases • Insight into the problems encountered by these patients and appropriate management strategies • Appreciation of Systemic Sclerosis

  3. Systemic lupus erythrematosus (SLE) (systemic inflammatory disorder – may affect organs such as heart, kydney, nervous system and lungs. Systemic Sclerosis - inflammation and fibrosis. ‘thickened skin’ Polymyosytis inflammatory myopathy (weakness of proximal musculature) Dermatomyosytis - (with associated skin rash) Diseases

  4. Focus on SLE and Sys Scl Very different diseases but do share come common themes – Skin – butterfly rash in SLE. Pigment, tight, beaking, microstomia in Sys Scl Raynauds – often worse in Sys Scl – digital ulceration Female more than male Small in number

  5. Themes cont’d Unkown aetiology Vasculitis Younger age group Fatigue Joint aches

  6. Education – paced Support – ‘groups or not groups’ – charities, individual support. Energy conservation – pacing. Life adjustment – occupation, home, family, aspirations, hopes, fears. Liason psychiatry – research in Sys Scl – Angelopoulos et al. (2001) Roca et al (1996) Sys Scl – Physio, OT Podiatry Pain management Ryanauds self management Management Strategies

  7. Drug therapy Immunosuprresion – typically steroids in early disease ( more use in SLE) Cylophosphamide/MethylPred– vasculitis, lung disease. Oral – cyclosporin, azathiprine, MTX. – for Raynauds (usually worse in Sys Scl. Nifedipine, Diltiazem – avoid beta blockers which may exacerbate.) Complimentary therapies for Raynauds – the ‘3 G’s Cont’d

  8. Brief Points • All connective tissue disease are not the same though they may share commonalities. • All patients with connective tissue diseases are not the same. • What we can offer as a minimum – -time -accurate information, up to date therapies -trust

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