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Case 6

Case 6. Basic clinical data. Archive case of I. Alvarado-Cabrero (Centro Medico, Mexico City) Hispanic male, 65 years Tumor of the urinary bladder TRUS with subsequent cystectomy. Your opinion, diagnosis?. Scorpio Euscorpius spec. Micropapillary urothelial carcinoma.

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Case 6

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  1. Case 6

  2. Basic clinical data • Archive case of I. Alvarado-Cabrero (Centro Medico, Mexico City) • Hispanic male, 65 years • Tumor of the urinary bladder • TRUS with subsequent cystectomy

  3. Your opinion, diagnosis?

  4. Scorpio Euscorpius spec

  5. Micropapillary urothelial carcinoma • cca 95 cases were published • Amin et al:Micropapillary variant of transitional cell carcinoma of the urinary bladder. Histologic pattern resembling ovarian papillary serous carcinoma. Am J Surg Pathol 18, 1994, 1224-1232 • WHO 2004-variant of TCC

  6. Basic clinico-pathologic features of micropapillary transitional cell carcinoma • Main age: 66 years • Male prevalence • Vascular invasion is usually present in time of diagnosis • Usually high-grade tumors • EMA/CK 7 usually positive • High stage in time of diagnosis, very bad prognosis (up to 12 months after establishing of the diagnosis)

  7. Differential diagnostics • High-grade „classic“ TCC • Inverted papilloma • „Nested“ variant of TCC

  8. Micropapilary ca vs. inverted papilloma

  9. Micropapillary ca-variants

  10. Micropapillary ca-variants

  11. Micropapilary ca vs. inverted papilloma

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