华东师范大学校级学术报告 清松化学学术系列讲座

1. 华东师范大学校级学术报告清松化学学术系列讲座华东师范大学校级学术报告清松化学学术系列讲座 报告题目: Exploiting the Extraordinarily Versatile N-O Bond: Rapid Synthesis of Biaryls, Carbazoles, Primary Aromatic Amines and Aziridines 报告人介: Prof . László Kürti 2010 Fall-, Tenure Track at UT Southwestern Medical Center; 2006-2010, Postdoctoral Studies, HarvardUniversity, Cambridge, MA; 2001-2006, Ph.D. in Organic Chemistry– University of Penns ylvania, Philadelphia, PA; 2001 June, Masters Degree in Organic Chemistry – University ofMissouri,Columbia, MO; 1998 June, Diploma in Chemistry–Lajos Kossuth University (now Univ. ofDebrecen), Debrecen, Hungary. 报告内容： The Kürti lab has been exploring several fundamentally new strategies for the transition-metal-free direct: (i) arylation of arenes; (ii); a-arylation of ketones, esters and amides; (iii) O-arylation of oximes; (iv) primary amination of arylboronic acids and (v) intramolecular C(sp2)-H amination of arenes. We have also discovered, in collaboration with the Falck (UTSW) and Ess labs (BYU), the Rh-catalyzed direct N-H/N-alkyl aziridination of olefins, a transformation that eluded synthetic chemists for decades. These methods have one thing in common: a weak N-O bond is cleaved in order to form a stronger C-C or C-N bond. In-depth experimental and computational studies have already identified the critical factors required for efficient alkyl-aryl, aryl-aryl, O-aryl and N-aryl bond-formation and led to several innovative and environmentally benign methods for the rapid preparation of structurally diverse arylated carbonyl compounds, functionalized biaryls as well as O- and N-heterocycles. 2014年5月30日（星期五）上午 9：15 华东师范大学中北校区化学馆A205报告厅 主办：华东师范大学化学系 上海市绿色化学与化工过程绿色化重点实验室 资助：华东师范大学自然科学系列学术活动专项经费 上海清松药业有限公司 报告时间与地点： 欢迎各位老师同学参加！