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Pulmonology – Chapter 2. Pulmonary Anatomy. Muscles of respiration Nervous control Blood supply Defense of the lungs. Respiratory Physiology. Basic functions of the respiratory system Mechanics of Breathing Lung volumes and capacities Exercise physiology Effects of aging.
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Pulmonary Anatomy • Muscles of respiration • Nervous control • Blood supply • Defense of the lungs
Respiratory Physiology • Basic functions of the respiratory system • Mechanics of Breathing • Lung volumes and capacities • Exercise physiology • Effects of aging
Signs & Symptoms of Pulmonary Disease (Table 2-4) • Anorexia • Bradycardia • Dec Breath sounds • Dec chest expansion • Chest pain • Coma • Confusion • Cough • Crackles, rales • Cyanosis • Diaphoresis • Digital clubbing • Dullness to percussion • Dyspnea • Fever • Hemoptysis • Hypercapnea • Hypoxemia • Mediastinal shift • Nasal secretions • Orthopnea • Paroxysmal nocturnal dyspnea • Pleural friction rub • Etc………
Cytologic - Hematologic • Sputum analysis • Green sputum 94% sensitive, 77% specific for high bacteria count that benefits from antibiotics • Hematological • ABG’s (later) • CBC (Lab Medicine) • Coagulation (Lab Medicine)
PFT’s • Volumes • TLC, VC, RV • Ventilation • VT, RR, Ve, Vd, VA • Common PFT measures • FVC, FEV1, FEV1/FVC ratio, PEFR, MVV • Diffusion studies • DLCO • Maximal Respiratory Pressures • MIP (PiMax); MEP (PeMax) • Chemical Control of Ventilation
ABG’s • PaO2 • PaCO2 • pH • SaO2 • HCO3- • Base excess / deficit
Pulse Oximetry • SpO2 • Ambulatory Oximetry
Electrocardiography • 12 lead - ? Right ventricular hypertrophy • Hypoxemia -> arrhythmias
Exercise testing • Pulmonary exercise testing • Walk tests
Pulmonary Imaging Studies • Fluoroscopy • Computed tomography • MRI • Ultrasonography
Nuclear Medicine • VQ Scans • Single photon Emission Computed Tomography • Positron Emission Tomography • Other Scintigraphic Imaging Studies • Gallium (high affinity for tumors)
Invasive Diagnostic Techniques • Pulmonary Angiography • Bronchography • Bronchoscopy • PercutaneousTransthoracic Needle Aspiration (biopsy) • Thoracocentesis • Thoracoscopy • Mediastinoscopy & Mediastinotomy • Open Lung Biopsy (Exploratory Thoracotomy)
Medical Management • Pharmacological therapy • Oxygen therapy • Airway adjuncts • Mechanical ventilation • Invasive • Non-invasive • Extracorporeal ventilation • Airway suctioning • Airway clearance • Incentive Spirometry • Smoking Cessation • Pulmonary Rehabiltation • Social Services
Surgical Interventions • Tracheotomy • Cricothyroidotomy • Excision of pulmonary emboli • Catheter / chest tube drain placement • Pulmonary resection / thoracotomy • Bullectomy • Lung Volume Reduction Surgery • Lung & Heart-Lung Transplansation • BroncialThermoplasty • Decortication • Pleurodesis • Pulmonary Metastasectomy • Tracheal Resection